A Human Adenovirus Enhances Preadipocyte Differentiation [PDF]
AbstractObjectives: Adenovirus 36 (Ad‐36) has been shown to increase adiposity in experimentally infected chickens, mice, and marmosets (nonhuman primates). Neutralizing antibodies to Ad‐36 are associated with obesity in humans. The metabolic and molecular mechanisms responsible for Ad‐36‐induced adipogenesis are unknown.
Sharada D, Vangipuram +4 more
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Human adenoviruses cause a wide spectrum of illnesses, including invasive infections, in immunocompromised hosts. We report a case of disseminated adenovirus infection following unrelated cord–blood transplantation in a 46-year-old male with a lymphoma ...
Akane Takamatsu +3 more
doaj +1 more source
STAT2 Knockout Syrian Hamsters Support Enhanced Replication and Pathogenicity of Human Adenovirus, Revealing an Important Role of Type I Interferon Response in Viral Control. [PDF]
Human adenoviruses have been studied extensively in cell culture and have been a model for studies in molecular, cellular, and medical biology. However, much less is known about adenovirus replication and pathogenesis in vivo in a permissive host because
Karoly Toth +8 more
doaj +1 more source
Human adenovirus causes infections with a very heterogeneous clinical picture, and children are often the most frequently affected group. Interest in adenovirus has increased with the 2022 outbreak of severe acute hepatitis of unknown etiology as human ...
Oana Săndulescu +5 more
doaj +1 more source
Effect of immunization with fetal cells on adenovirus-12 oncogenesis [PDF]
The effect of immunization with hamster fetal cells on the tumor induction by adnovirus type 12 was studied by in vivo and in vitro. The immunization with lO-day old fetal cells showed a recognizable inhibition on the tumor induction by adenovirus type ...
Abe, Shinji
core +1 more source
Development of a WNT-selective oncolytic adenovirus for imaging the therapy of colorectal cancers. [PDF]
PhDIntroduction: The concept of oncolytic adenoviruses has been validated in preclinical studies but clinical trials have demonstrated that the virus spread remains limited and the virus fails to infect all cancer cells in a tumour.
Peerlinck, Inge D. L.
core +4 more sources
Adenovirus Early Proteins and Host Sumoylation
The human adenovirus genome is transported into the nucleus, where viral gene transcription, viral DNA replication, and virion assembly take place. Posttranslational modifications by small ubiquitin-like modifiers (SUMOs) are implicated in the regulation
Sook-Young Sohn, Patrick Hearing
doaj +1 more source
Presence of adenovirus species C in infiltrating lymphocytes of human sarcoma. [PDF]
Human adenoviruses are known to persist in T-lymphocytes of tonsils, adenoids and intestinal tract. The oncogenic potential of different adenovirus types has been widely studied in rodents, in which adenovirus inoculation can induce multiple tumors such ...
Karin Kosulin +4 more
doaj +1 more source
Monitoring human adenovirus loads in bronchoalveolar lavage fluid in non-immunocompromised children with human adenovirus pneumonia. [PDF]
Human adenoviruses (HAdVs) are prevalent pathogens responsible for respiratory infections. In this study, we examined the relationship between adenovirus viral loads in bronchoalveolar lavage fluid (BALF) and the severity of adenovirus pneumonia in children.The medical records of patients admitted to Guangzhou Women and Children's Medical Center with ...
Zeng S +7 more
europepmc +3 more sources
Antibody to human adenovirus early antigens during acute adenovirus infections [PDF]
The antibody (Ab) response to human adenovirus (AV) early antigens (EA) in acute AV infections was studied by the immunoperoxidase antibody technique for determining virus-specific immunoglobulin G (IPA-IgG). AV-EA-Ab appeared about 5 days after the onset of clinical symptoms, reached a peak 15 to 30 days later, and declined in titer after a few months.
G, Gerna +4 more
openaire +2 more sources

