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Background Human adenovirus can cause morbidity and mortality in immunocompromised patients after allogeneic stem cell transplantation. Reconstitution of adenovirus-specific CD4+ T cells has been reported to be associated with sustained protection from ...
Maarten L. Zandvliet +12 more
doaj +1 more source
Research progress on human adenovirus sepsis. [PDF]
Human adenovirus is a significant viral pathogen causing lower respiratory tract infections in children, prone to developing into severe pneumonia and systemic inflammation with a high mortality rate, especially in immunocompromised children, drawing widespread attention worldwide.
Jianhua W +5 more
europepmc +4 more sources
Brain tumors induced in rats by human adenovirus type 12 [PDF]
Oncogenesis of human adenovirus type 12 in the brain of rats was examined. Newborn rats of Sprague-Dawley and Donryu strains were injected intracranially with human adenovirus type 12. The incidence of intracranial tumors was 91% (30/33) in
Ogawa, Katsuo +5 more
core +1 more source
A host non-coding RNA, nc886, plays a pro-viral role by promoting virus trafficking to the nucleus
Elucidation of the interplay between viruses and host cells is crucial for taming viruses to benefit human health. Cancer therapy using adenovirus, called oncolytic virotherapy, is a promising treatment option but is not robust in all patients.
Enkhjin Saruuldalai +16 more
doaj +1 more source
Human adenovirus associated with severe cold agglutinin syndrome: a rare complication in Pediatrics [PDF]
Objective: The objectives of this study were to describe the first pediatric case of cold agglutinin syndrome (CAS) triggered by human adenovirus and review the literature.
Julia Loureiro Sion +3 more
doaj +1 more source
A New Bovine Adenovirus Related to Human Adenovirus.
SummaryA second bovine adenovirus has been isolated. The virus is antigenically similar to a human virus as determined by 1) neutralization with human gamma globulin and human adult sera, and 2) possession of a complement fixing antigen similar to that of the human adenovirus. The related type of human adenovirus remains unknown.
M, KLEIN, J, ZELLAT, T C, MICHAELSON
openaire +2 more sources
The Structure of the Human Adenovirus 2 Penton [PDF]
The adenovirus penton, a noncovalent complex of the pentameric penton base and trimeric fiber proteins, comprises the vertices of the adenovirus capsid and contains all necessary components for viral attachment and internalization. The 3.3 A resolution crystal structure of human adenovirus 2 (hAd2) penton base shows that the monomer has a basal ...
Zubieta, Chloe +3 more
openaire +3 more sources
Immunological Study of Reconstructed Common Ancestral Sequence of Adenovirus Hexon Protein
Aim: To reconstruct the ancestral sequence of human adenoviral hexon protein by combining sequence variations and structural information. And to provide a candidate hexon protein for developing new adenoviral vector capable of escaping the pre-existing ...
Yingchen Wang +12 more
doaj +1 more source
Adenovirus 38: a New Human Adenovirus Species of Subgenus D
From the stool of a Dutch girl, a new virus (LJ) was isolated that by morphological, biological, and immunological criteria was a human adenovirus. Because of its hemagglutinating activity for rat and human red blood cells and its DNA restriction enzyme pattern, the virus was classified as a member of subgenus D. It was distinct in neutralization tests
de Jong, JC +6 more
openaire +3 more sources
Requirements for receptor engagement during infection by adenovirus complexed with blood coagulation factor X [PDF]
Human adenoviruses from multiple species bind to coagulation factor X (FX), yet the importance of this interaction in adenovirus dissemination is unknown.
Angela C Bradshaw +37 more
core +3 more sources

