Adenovirus 36 DNA in human adipose tissue [PDF]
Recent studies have suggested a possible correlation between obesity and adenovirus 36 (Adv36) infection in humans. As information on adenoviral DNA presence in human adipose tissue are limited, we evaluated the presence of Adv36 DNA in adipose tissue of 21 adult overweight or obese patients. Total DNA was extracted from adipose tissue biopsies.
Ponterio, E +7 more
openaire +3 more sources
Adenoviral based gene therapy for cancer in human and animals: a review [PDF]
Adenovirus vector is the most common used vector in clinical gene therapy. The development of adenovirus from the first generation until the helper-dependent adenovirus vector has greatly reduced toxicity and immunogenicity.
Allaudin, Zeenathul Nazariah +2 more
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Adenovirus vector-specific T cells demonstrate a unique memory phenotype with high proliferative potential and coexpression of CCR5 and integrin α\(_4\)β\(_7\) [PDF]
Background: The Step Study was a randomized trial to reduce HIV infection through vaccination with an adenovirus type 5-based gag/pol/nef construct; analysis following early cessation of the trial revealed an excess of HIV seroconversion in Ad5 ...
Chakupurakal, Geothy +4 more
core +1 more source
Human Adenovirus Surveillance — United States, 2003–2016 [PDF]
Human adenoviruses (HAdVs) are nonenveloped, double-stranded DNA viruses in the family Adenoviridae; seven species (A-G) and >60 genotypes are known to cause human infection (1). Clinical manifestations associated with HAdV infection include fever, acute respiratory illness, gastroenteritis, and conjunctivitis.
Binder, Alison M. +7 more
openaire +2 more sources
Fluorescence-guided surgery of a highly-metastatic variant of human triple-negative breast cancer targeted with a cancer-specific GFP adenovirus prevents recurrence. [PDF]
We have previously developed a genetically-engineered GFP-expressing telomerase-dependent adenovirus, OBP-401, which can selectively illuminate cancer cells.
Bouvet, Michael +9 more
core +2 more sources
Survivin a radiogenetic promoter for glioblastoma viral gene therapy independently from CArG motifs [PDF]
BACKGROUND: Radiogenetic therapy is a novel approach in the treatment of cancer, which employs genetic modification to alter the sensitivity of tumor cells to the effect of applied radiation.
Arafat WO +16 more
core +2 more sources
Association of Adenovirus Infection with Human Obesity [PDF]
AbstractDHURANDHAR, NIKHIL V, PUSHPA R KULKARNI, SHARAD M AJINKYA, ABHAYA A SHERIKAR, RICHARD L ATKINSON. Association of adenovirus infection with human obesity.We previously reported that chickens infected with the avian adenovirus SMAM‐1 developed a unique syndrome characterized by excessive intra‐abdominal fat deposition accompanied by paradoxically
N V, Dhurandhar +4 more
openaire +2 more sources
Human Adenovirus Associated with Severe Respiratory Infection, Oregon, USA, 2013–2014
Several human adenoviruses (HAdVs) can cause respiratory infections, some severe. HAdV-B7, which can cause severe respiratory disease, has not been recently reported in the United States but is reemerging in Asia.
Magdalena Kendall Scott +8 more
doaj +1 more source
Diarrhea is the commonest cause of morbidity and mortality in many resource-limited countries including Tanzania among children below five years of age.
Delfina R. Msanga +9 more
doaj +1 more source
Inhibition of adenovirus serotype 14 infection by octadecyloxyethyl esters of (S)-[(3-hydroxy-2-phosphonomethoxy)propyl]- nucleosides in vitro. [PDF]
On September 22, 2008, a physician on Prince of Wales Island, Alaska, notified the Alaska Department of Health and Social Services (ADHSS) of an unusually high number of adult patients with recently diagnosed pneumonia (n = 10), including three persons ...
Barnard, Dale L +8 more
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