Results 31 to 40 of about 498,853 (259)

Automation in Human-Machine Networks: How Increasing Machine Agency Affects Human Agency [PDF]

, 2017
Efficient human-machine networks require productive interaction between human and machine actors. In this study, we address how a strengthening of machine agency, for example through increasing levels of automation, affect the human actors of the networks. Findings from case studies within air traffic management, crisis management, and crowd evacuation
Følstad, Asbjørn, Engen, Vegard, Haugstveit, Ida Maria, Pickering, J. Brian   +3 more
openaire   +3 more sources

Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra, Maria McCarthy, Michael Takagi, Cinzia De Luca   +3 more
wiley   +1 more source

The emancipation of the language learner

Studies in Second Language Learning and Teaching, 2012
The general trend in language education over the years has been to ascribe to language learners increasing power and responsibility for their own learning. While this is commendable, the autonomy of learners is still constrained by views of language that
Diane Larsen-Freeman
doaj   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

The Pilgrim’s Progress or Regress? The Case of Transhumanism and Deification

Religions
Transhumanism presents a view of human progress by transcending the human, regarding finitude and suffering to be fundamental problems that must be overcome by radical bioenhancement technologies.
Kimbell Kornu
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The EU Response to the Presence of Nitrosamine Impurities in Medicines

Frontiers in Medicine, 2021
The unexpected detection of nitrosamine impurities in human medicines has recently seen global regulators act to understand the risks of these contaminations to patients and to limit their presence.
Robin Ruepp, Roland Frötschl, Robert Bream, Maria Filancia, Thomas Girard, Andrei Spinei, Martina Weise, Rhys Whomsley   +7 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Divine Determinism to Digital Determinism: The Paradigm Shift of Fate in the 21st Century [PDF]

Pharos Journal of Theology
This article investigates the theoretical reorientation of the term 'destiny' from the classical theological understanding of divine determinism—anchored in natural law philosophy—to the contemporary model of digital determinism arising from the ...
Fernanda Putra Adela, Try Adhi Bangsawan   +1 more
doaj   +1 more source