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The Pilgrim’s Progress or Regress? The Case of Transhumanism and Deification
ReligionsTranshumanism presents a view of human progress by transcending the human, regarding finitude and suffering to be fundamental problems that must be overcome by radical bioenhancement technologies.
Kimbell Kornu
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Strategic Directions for Human Development in Papua New Guinea
, 2007 There is an emerging consensus in Papua New Guinea (PNG) -- both at the governmental level and among civil society more generally -- that human development outcomes are far less than satisfactory and that service provision in many parts of the country is
World Bank +2 more
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African Agency in a Changing Security Environment: Sources, Opportunities and Challenges [PDF]
, 2013 This special issue contributes to the growing debate on the nature and limits of African agency. It does so by focusing on the possibilities of and constraints on agency in the security sphere.
Hammerstad, Anne
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
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Viabilité, probabilités, induction
Tracés, 2013 While probability calculus helps favour the credence in a future occurrence, operational research prescribes a list of controls aimed at a given objective, generally in optimizing a given criterion.
Noël Bonneuil
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
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The book explores the multi-faceted nature of contemporary reflections on agency, focusing on various discursive practices that shape the posthumanist approach to the relationship between the human and non-human world from a planetary perspective.
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, 2010 The feeling of controlling events through one's actions is fundamental to human experience, but its neural basis remains unclear. This 'sense of agency' (SoA) can be measured quantitatively as a temporal linkage between voluntary actions and their ...
Ruge, Diane +9 more
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