Results 11 to 20 of about 552,451 (291)

Single-center analysis of the inappropriate use of human albumin and nutritional support in hospitalized patients with hypoproteinemia in China [PDF]

Journal of International Medical Research, 2021
Background This study used single-center analysis of human serum albumin clinical usage and enteral-parenteral nutritional support to establish clinical application standards for the rational use of human serum albumin.
Jin Zhang, ZheTao Zhang, TianLu Shi
doaj   +2 more sources

Extended plasma half-life of albumin-binding domain fused human IgA upon pH-dependent albumin engagement of human FcRn in vitro and in vivo

mAbs, 2021
Albumin has a serum half-life of 3 weeks in humans. This feature can be used to improve the pharmacokinetics of shorter-lived biologics. For instance, an albumin-binding domain (ABD) can be used to recruit albumin.
Simone Mester, Mitchell Evers, Saskia Meyer, Jeannette Nilsen, Victor Greiff, Inger Sandlie, Jeanette Leusen, Jan Terje Andersen   +7 more
doaj   +1 more source

Non inferiority trial of Channa striata extract on endothelial glycocalyx layer protection in septic patient: a prospective cohort study [PDF]

Pharmacia, 2023
Introduction: Sepsis causes significant damage to the endothelial glycocalyx layer, which albumin can protect against. Unfortunately, human albumin is quite expensive, so cheaper substitutes must be found without sacrificing effectiveness.
Septian Adi Permana, Hartono Hartono, Bambang Purwanto, Dono Indarto   +3 more
doaj   +3 more sources

Human albumin prevents 6-hydroxydopamine-induced loss of tyrosine hydroxylase in in vitro and in vivo. [PDF]

PLoS ONE, 2012
Human albumin has recently been demonstrated to protect brain neurons from injury in rat ischemic brain. However, there is no information available about whether human albumin can prevent loss of tyrosine hydroxylase (TH) expression of dopaminergic (DA ...
Li-Juan Zhang, Yue-Qiang Xue, Chun Yang, Wei-Hua Yang, Long Chen, Qian-Jin Zhang, Ting-Yu Qu, Shile Huang, Li-Ru Zhao, Xiao-Min Wang, Wei-Ming Duan   +10 more
doaj   +1 more source

Structure and Functions of Human Serum Albumin in Normal Conditions and in Patients with Liver Cirrhosis

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2022
The aim: to highlight the main points of albumin synthesis, posttranslational modifications and functions in normal conditions and in patients with liver cirrhosis.Key points. Albumin is the most abundant protein in blood plasma.
A. A. Turkina, M. V. Mayevskaya, M. S. Zharkova, V. T. Ivashkin   +3 more
doaj   +1 more source

PEGylated Human Serum Albumin: Review of PEGylation, Purification and Characterization Methods [PDF]

Advanced Pharmaceutical Bulletin, 2016
Human serum albumin (HSA) is a non-glycosylated, negatively charged protein (Mw: about 65-kDa) that has one free cystein residue (Cys 34), and 17 disulfide bridges that these bridges have main role in its stability and longer biological life-time (15 to ...
Parvin Akbarzadehlaleh, Mona Mirzaei, Mahdiyeh Mashahdi-Keshtiban, Karim Shamsasenjan, Hamidreza Heydari   +4 more
doaj   +1 more source

Comparative analysis of quality attributes of a human albumin preparation with a modified stabilising composition

Биопрепараты: Профилактика, диагностика, лечение, 2023
Scientific relevance. The national and international human albumin preparations registered in the Russian Federation mainly differ in their excipient compositions.
M. V. Tomilin, T. V. Korotkova, P. A. Loginov   +2 more
doaj   +1 more source

The Influence of Oxidative Stress on Serum Albumin Structure as a Carrier of Selected Diazaphenothiazine with Potential Anticancer Activity

Pharmaceuticals, 2021
Albumin is one of the most important proteins in human blood. Among its multiple functions, drug binding is crucial in terms of drug distribution in human body.
Małgorzata Maciążek-Jurczyk, Beata Morak-Młodawska, Małgorzata Jeleń, Wiktoria Kopeć, Agnieszka Szkudlarek, Aleksandra Owczarzy, Karolina Kulig, Wojciech Rogóż, Jadwiga Pożycka   +8 more
doaj   +1 more source

Cellular specificity of the blood-CSF barrier for albumin transfer across the choroid plexus epithelium. [PDF]

PLoS ONE, 2014
To maintain the precise internal milieu of the mammalian central nervous system, well-controlled transfer of molecules from periphery into brain is required.
Shane A Liddelow, Katarzyna M Dzięgielewska, Kjeld Møllgård, Sophie C Whish, Natassya M Noor, Benjamin J Wheaton, Renate Gehwolf, Andrea Wagner, Andreas Traweger, Hannelore Bauer, Hans-Christian Bauer, Norman R Saunders   +11 more
doaj   +1 more source

Evaluation of intravenous hydroxylethyl starch, intravenous albumin 20%, and oral cabergoline for prevention of ovarian hyperstimulation syndrome in patients undergoing ovulation induction

Journal of Research in Medical Sciences, 2015
Background: The purpose of this study was to compare the three different strategies, intravenous (IV) hydroxylethyl starch (HES), IV human albumin (HA), and oral Cabergoline (Cb) in the prevention of ovarian hyperstimulation syndrome (OHSS).
Ataollah Ghahiri, Neda Mogharehabed, Minoo Movahedi, Naeimehossadat Hosseini   +3 more
doaj   +1 more source