Results 21 to 30 of about 595,824 (293)

The Influence of Oxidative Stress on Serum Albumin Structure as a Carrier of Selected Diazaphenothiazine with Potential Anticancer Activity

open access: yesPharmaceuticals, 2021
Albumin is one of the most important proteins in human blood. Among its multiple functions, drug binding is crucial in terms of drug distribution in human body.
Małgorzata Maciążek-Jurczyk   +8 more
doaj   +1 more source

Reversible Dimerization of Human Serum Albumin

open access: yesMolecules, 2020
Pulsed Dipolar Spectroscopy (PDS) methods of Electron Paramagnetic Resonance (EPR) were used to detect and characterize reversible non-covalent dimers of Human Serum Albumin (HSA), the most abundant protein in human plasma.
Alexey Chubarov   +8 more
doaj   +1 more source

Albumin Oxidation Status in Sepsis Patients Treated With Albumin or Crystalloids

open access: yesFrontiers in Physiology, 2021
Inflammation and oxidative stress characterize sepsis and determine its severity. In this study, we investigated the relationship between albumin oxidation and sepsis severity in a selected cohort of patients from the Albumin Italian Outcome Study ...
Matteo Bonifazi   +21 more
doaj   +1 more source

Spectroscopic Technique-Based Comparative Investigation on the Interaction of Theaflavins with Native and Glycated Human Serum Albumin

open access: yesMolecules, 2019
Theaflavin is a kind of multi-pharmacological and health beneficial black tea factor. The aim of this study is to investigate the mechanisms by which theaflavin interacts with glycosylated and non-glycosylated serum albumins and compares their binding ...
Jinhui Xu   +3 more
doaj   +1 more source

Carboxylated Poly-l-Lysine as a Macromolecular Cryoprotective Agent Enables the Development of Defined and Xeno-Free Human Sperm Cryopreservation Reagents

open access: yesCells, 2021
In human sperm cryopreservation, test yolk buffer and human serum albumin have been used as permeating macromolecular-weight cryoprotectants. In clinical reproductive medicine, human serum albumin is frequently used because of low risks of zoonoses and ...
Hiroki Takeuchi   +13 more
doaj   +1 more source

Real-world experience with long-term albumin in patients with cirrhosis and ascites

open access: yesJHEP Reports
Background & Aims: Long-term albumin (LTA) is currently standard of care for patients with decompensated cirrhosis in many Italian hepatology centres.
Enrico Pompili   +19 more
doaj   +1 more source

99mTc-GSA scintigraphy for assessing the functional volume ratio of the future liver remnant in the routine practice of liver resection

open access: yesSurgery Open Science, 2022
Background: The significance of incorporating regional functional heterogeneity assessment by liver scintigraphy into the calculation of the future liver remnant has been reported.
Masatake Iida, MD, PhD   +6 more
doaj   +1 more source

Mathematical modeling of interactions of cabergoline with human serum albumin for biosensing of human serum albumin

open access: yesSensing and Bio-Sensing Research, 2019
In this work, we are going to study the interactions of cabergoline (CBG) with human serum albumin (HSA) by mathematical modeling of voltammetric and spectroscopic data.
Ali R. Jalalvand   +5 more
doaj   +1 more source

Human microglial cells synthesize albumin in brain. [PDF]

open access: yesPLoS ONE, 2008
Albumin, an abundant plasma protein with multifunctional properties, is mainly synthesized in the liver. Albumin has been implicated in Alzheimer's disease (AD) since it can bind to and transport amyloid beta (Abeta), the causative agent of AD; albumin ...
Sung-Min Ahn   +9 more
doaj   +1 more source

A Comprehensive Spectroscopic Analysis of the Ibuprofen Binding with Human Serum Albumin, Part II

open access: yesScientia Pharmaceutica, 2021
Human serum albumin (HSA) is the most abundant human plasma protein. HSA plays a crucial role in many binding endos- and exogenous substances, which affects their pharmacological effect.
Anna Ploch-Jankowska   +2 more
doaj   +1 more source

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