Results 111 to 120 of about 12,614,860 (303)

The short and long-term efficacy of nurse-led interventions for improving blood pressure control in people with hypertension in primary care settings: a systematic review and meta-analysis

BMC Primary Care
Background Previous systematic reviews suggest that nurse-led interventions improve short-term blood pressure (BP) control for people with hypertension. However, the long-term effects, adverse events, and appropriate target BP level are unclear.
Masami Ito, Aran Tajika, Rie Toyomoto, Hissei Imai, Masatsugu Sakata, Yukiko Honda, Sanae Kishimoto, Memori Fukuda, Noboru Horinouchi, Ethan Sahker, Toshi A. Furukawa   +10 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

AI teammates and human performance : evidence for commitment deficits

Published online: 05 November 2025Human–AI teams (HATs) often underperform despite growing AI capabilities, with most explanations centering on coordination and communication failures or misjudgment of AI capabilities. This research investigates teammate
WINTER, Jonathan
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Task-sharing to promote caregiver mental health, positive parenting practices, and violence prevention in vulnerable families in Sierra Leone: a pilot feasibility study

BMC Psychiatry
Background The prevalence of household violence in low- and middle-income countries (LMICs) is high, and exposure to violence has significant adverse effects on both mental health and child development across generations.
Alethea Desrosiers, Indrani Saran, Ariana M. Albanese, Cara M. Antonaccio, Sarah E. Neville, Rebecca Esliker, Musu Jambai, Mahmoud Feika, Theresa S. Betancourt   +8 more
doaj   +1 more source

Is Britain Fairer?: The State of Equality and Human Rights in Britain [PDF]

, 2015
This is our five-yearly report on equality and human rights progress in Great Britain. The report sets out our findings and the challenges for the future in the following areas: - education and learning - work, income and the economy - health and care -
Equality and Human Rights Commission,
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Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Associations between recreational cannabis legalization and cannabis use disorder treatment outcomes in California, 2010–2021

Journal of Cannabis Research
Background Despite extensive research on the broader effects of recreational cannabis legalization (RCL), limited attention has been given to its impact on cannabis use disorder (CUD) treatment outcomes.
Brittany Bass, Howard Padwa, Dhruv Khurana, Darren Urada   +3 more
doaj   +1 more source

THE UTILITARIAN FOUNDATIONS OF THE ECONOMIC APPROACH TO HUMAN BEHAVIOR. [PDF]

The economic approach to the study of human behavior has been presented by its foremost representative as the most effective method of studying social phenomena.
Jimena Hurtado
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