Results 201 to 210 of about 17,541,441 (365)

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

Human touch? Acoustical analysis of ancient music reconstructs tuning and intonation, elucidating aspects of human behavior. [PDF]

Sci Adv
Baciu DC.
europepmc   +1 more source

Frictional Behavior and Surface Failure of Human Enamel [PDF]

, 1973
John M. Powers, R.G. Craig, K. C. Ludema
openalex   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Residential environment, human behavior and socio-economic status in transmission of cutaneous leishmaniasis in central Iran. [PDF]

Sci Rep
Heidari A, Dashtaki NM, Mizbani S, Rejali M, Maracy MR.   +4 more
europepmc   +1 more source

Retracted: Sports Deep Learning Method Based on Cognitive Human Behavior Recognition. [PDF]

Comput Intell Neurosci, 2023
Intelligence And Neuroscience C.
europepmc   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Functional Connectivity of the Scene Processing Network at Rest Does Not Reliably Predict Human Behavior on Scene Processing Tasks. [PDF]

eNeuro
Watson DM, Andrews TJ.
europepmc   +1 more source

On power and its corrupting effects: the effects of power on human behavior and the limits of accountability systems. [PDF]

Commun Integr Biol, 2023
Tobore TO.
europepmc   +1 more source

INDIVIDUALITY AS EXHIBITED BY INBRED ANIMALS; ITS IMPLICATIONS FOR HUMAN BEHAVIOR

, 1962
Roger J. Williams, Richard B. Pelton, Frank L. Siegel   +2 more
openalex   +1 more source