Results 121 to 130 of about 3,861,359 (218)

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

"It's Shaking Your Entire Construction as a Human Being": A Qualitative Analysis on Epistemic Injustice and Medical Gaslighting Consequences in Patients Living with Chronic Pain. [PDF]

J Med Philos
Côte CI.
europepmc   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Correction: Past and current status of adolescents living with HIV in South Africa, 2005–2017

BMC Research Notes
Inbarani Naidoo, Sinovuyo Takatshana, Ronel Sewpaul, Sean Jooste, Zhou Siyanai, Goitseone Maseko, Sizulu Moyo, Khangelani Zuma, Musawenkosi Mabaso, Zungu Nompumelelo   +9 more
doaj   +1 more source

'Even if you are guilty, you're still a human being': the impact of stigma on dignity and quality of healthcare from the perspective of people detained in police custody in England. [PDF]

Health Justice
Addison M, Mulrine S, McKinnon I, Rees G.   +3 more
europepmc   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

<i>"I was treated like a human being"</i>: factors influencing women's preference for traditional birth attendants in Nigeria. [PDF]

Front Glob Womens Health
Yalley AA, Sanusi Gumbi K.
europepmc   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

"Insight into who you are as a human being": Perceptions of the Utility and Usability of a Values Assessment Tool (VAsT) for Women With Metastatic Breast Cancer. [PDF]

Cancer Control
Crowder R, Crowder V, Fariman S, Joglekar N, Anderson D, Miller J, Walker S, Ray EM, Ford-Pierce S, Reeve BB, Bennett A, Mazor M, Deal AM, Coombs LA.   +13 more
europepmc   +1 more source