The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Identity as Theory and Method for Ethnic Studies [PDF]
, 1986 The question of identity is fundamental to human life. Who am I, as a biological and psychological being; as a member of a human group with a particular style and history; as a participant in the common human values, perceptions, and processes which ...
Hatfield, John
core +1 more source
Антибиотики и Химиотерапия, 2020 The spread of Vibrio cholerae strains with multiple antibiotic resistances makes it necessary to search for alternative antibiotics that are effective against the cholera pathogen.
A. V. Tyurina +6 more
doaj
A balance between putting on the researcher's hat and being a fellow human being: a researcher perspective on informal carer involvement in health and social care research. [PDF]
Health Res Policy Syst, 2022 Malm C +3 more
europepmc +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Composite Indices of Human Well-being: Past, Present, and Future [PDF]
human well-being, composite well-being indices, income per capita, Human Development Index, Physical Quality of Life ...
McGillivray, Mark, Noorbakhsh, Farhad
core
The EU's Hospitality and Welcome Culture: Conceiving the "No Human Being Is Illegal" Principle in the EU Fundamental Freedoms and Migration Governance. [PDF]
Hum Rights Rev, 2022 Aliu A, Aliu D.
europepmc +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The Sufferings of the Biblical Job as an Icon of Postmodernity: The 'loneliness' of God and the human being in a consumerist paradise. [PDF]
J Relig Health, 2023 Stala J, Osewska E, Bochenek K.
europepmc +1 more source