FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
"Treat Them Like a Human Being…They are Somebody's Somebody": Providers' Perspectives on Treating Patients in the Emergency Department After Self-Injurious Behavior. [PDF]
Community Ment Health J, 2023 Cullen SW +7 more
europepmc +1 more source
WITTGENSTEIN ON SUBJECTIVITY: THE METAPHYSICAL SUBJECT IN THE TRACTATUS AND THE HUMAN BEING IN THE INVESTIGATIONS [PDF]
, 2010 Hao Tang
openalex +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Радиационная гигиена, 2015 The article describes the experience of the Administration of the Federal Service for Surveillance on Consumer Rights Protection and Human Well-being in Sakhalin Region in organizing prevention of conditions that endanger the public radiation safety ...
B. B. Darizhapov +3 more
doaj
Human Being Detection from UWB NLOS Signals: Accuracy and Generality of Advanced Machine Learning Models. [PDF]
Sensors (Basel), 2022 Moro G, Di Luca F, Dardari D, Frisoni G.
europepmc +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Радиационная гигиена, 2017 The conducted comparative analysis of the medical exposure of the population of Russian Federation and one of its administrative territories reveals the leading importance for the medical exposure reduction of the renewing of X-ray equipment and the ...
V. G. Morozov +2 more
doaj
'You have a little human being kicking inside you and an unbearable pain of knowing there will be a void at the end': A meta-ethnography exploring the experience of parents whose baby is diagnosed antenatally with a life limiting or life-threatening condition. [PDF]
Palliat Med, 2023 Tatterton MJ, Fisher MJ.
europepmc +1 more source