The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Well-being: the heart of being human, the art of being whole [PDF]
Westfall, Mary
core +1 more source
Inter-species and individualized biotransformation of five saponins by human being- and mouse-derived fecal microbiota. [PDF]
Wei W +8 more
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Being Together: Dietrich Bonhoeffer on Human Being and Theological Ethics [PDF]
Dahl, Darren E.
core +1 more source
Correction: Past and current status of adolescents living with HIV in South Africa, 2005–2017
Inbarani Naidoo +9 more
doaj +1 more source
Marty's last publication: A giant human being with a passion to cure children. [PDF]
Fisher DE.
europepmc +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
'You come as a human being…': exploring sense of equality in arts interventions through an ethnographic study of Shared Reading. [PDF]
Kristensen MM +3 more
europepmc +1 more source

