Results 81 to 90 of about 3,861,359 (218)

The COVID-19 Epidemic Process in Long-Term Care Facilities in Moscow

Эпидемиология и вакцинопрофилактика
Relevance. COVID-19 remains an urgent disease for long-term care institutions (LTCI), because local outbreaks of COVID-19 continue to be registered in 2022 and in 2023.Aims.
N. G. Davidova, S. V. Ugleva, S. V. Shabalina   +2 more
doaj   +1 more source

SARS-CoV-19 Mutations: is a Blessing or a Curse for Human Being? [PDF]

Ethiop J Health Sci, 2022
Jadali Z.
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Hemophilus meningitis – Current Aspects of Epidemiology and Prevention: a Descriptive Review

Эпидемиология и вакцинопрофилактика
Relevance. H. influenzae is a common cause of bacterial meningitis in children worldwide. Significant data have been accumulated worldwide on the use of H. influenzae type b conjugate vaccines over the past three decades.
M. I. Gritsay, I. S. Koroleva, M. A. Koroleva   +2 more
doaj   +1 more source

Agronomic bio-fortification of wheat (Triticum aestivum L.) to alleviate zinc deficiency in human being. [PDF]

Rev Environ Sci Biotechnol, 2023
Singh S, Kaur J, Ram H, Singh J, Kaur S.
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

The Role of Neuroergonomics in the Design of Personalized Prosthesis: Deepening the Centrality of Human Being. [PDF]

Front Neurorobot, 2022
Corti L.
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Taking the principle of the primacy of the human being seriously. [PDF]

Med Health Care Philos, 2021
Różyńska J.
europepmc   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source