Results 41 to 50 of about 2,100,730 (306)

Evaluation of the stability of human erythropoietin in samples for radioimmunoassay [PDF]

open access: yes, 1988
Radioimmunoassays for erythropoietin are limited so far to a few specialized laboratories and this requires transport and storage of samples. We therefore tested the stability of immunoreactive erythropoietin in serum and plasma samples obtained from a ...
Bauer, Christian   +5 more
core   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Lapatinib-induced enhancement of mitochondrial respiration in HER2-positive SK-BR-3 cells: mechanism revealed by analysis of proteomic but not transcriptomic data

open access: yesFrontiers in Molecular Biosciences
Dual inhibitors of HER2 and EGFR, such as lapatinib, have shown significant efficacy for the therapy of HER2-positive breast cancer. Previous experiments showed that in cell cultures, the efficacy of lapatinib was significantly reduced by exposure to ...
Dmitry Kamashev   +15 more
doaj   +1 more source

The influence of portal blood upon lipid metabolism in normal and diabetic dogs and baboons [PDF]

open access: yes, 1975
It has been reported that hyperlipidemia can be alleviated in human beings with an end to side portacaval shunt. Understanding the mechanism of the effect has important implications, including the possibility of devising other ways of lowering serum ...
Lee, IY   +3 more
core  

The proinflammatory activity of recombinant serum amyloid A is not shared by the endogenous protein in the circulation.

open access: yes, 2010
OBJECTIVE: Elevated serum levels of the acute-phase protein serum amyloid A (SAA) are a marker for active rheumatoid arthritis (RA), and SAA can also be found in the tissues of patients with active RA.
Björkman, Lena   +5 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Cholesterol Concentration in Human Serum and Blood Cells.

open access: yesExperimental Biology and Medicine, 1960
Summary1) Direct analyses of cholesterol in blood cells from 38 men yielded average value of 137.7 mg/100 ml and there was no correlation with serum values in these samples. Standard deviation of these cell values was only 6.5 and part of this small value is accounted for by analytical error. Indirect estimates agreed closely but variability was larger.
M, MANCINI, A, KEYS
openaire   +2 more sources

Disposable Integrated Microfluidic Biochip for Blood Typing by Plastic Microinjection Moulding [PDF]

open access: yes
Blood typing is the most important test for both transfusion recipients and blood donors. In this paper, a low cost disposable blood typing integrated microfluidic biochip has been designed, fabricated and characterized.
Chong H. Ahn   +4 more
core   +1 more source

Culture of human cell lines by a pathogen-inactivated human platelet lysate [PDF]

open access: yes, 2015
Alternatives to the use of fetal bovine serum (FBS) have been investigated to ensure xeno-free growth condition. In this study we evaluated the efficacy of human platelet lysate (PL) as a substitute of FBS for the in vitro culture of some human cell ...
Bonanno, G   +8 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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