MA104 cell line is permissive for human bocavirus 1 infection [PDF]
Journal of VirologyHuman bocavirus 1 (HBoV1) has appeared as an emerging pathogen, causing mild to life-threatening respiratory tract infections, acute otitis media, and encephalitis in young children and immunocompromised individuals.
Jielin Tang +12 more
doaj +4 more sources
A Comprehensive RNA-seq Analysis of Human Bocavirus 1 Transcripts in Infected Human Airway Epithelium [PDF]
Viruses, 2019 Human bocavirus 1 (HBoV1) infects well-differentiated (polarized) human airway epithelium (HAE) cultured at an air-liquid interface (ALI). In the present study, we applied next-generation RNA sequencing to investigate the genome-wide transcription ...
Wei Zou +5 more
doaj +4 more sources
NS1-mediated DNMT1 degradation regulates human bocavirus 1 replication and RNA processing. [PDF]
PLoS PathogensMethylation of the DNA genome plays an important role in viral gene inactivation. However, the role of DNA methylation in human bocavirus (HBoV) remains unclear.
Shuangkang Qin +10 more
doaj +4 more sources
The Burden of Human Bocavirus 1 in Hospitalized Children With Respiratory Tract Infections [PDF]
Journal of the Pediatric Infectious Diseases Society, 2023 Abstract Background Human bocavirus 1 (HBoV1) is frequently codetected with other viruses, and detected in asymptomatic children. Thus, the burden of HBoV1 respiratory tract infections (RTI) has been unknown.
Jalving, Hedda Trømborg +7 more
openaire +3 more sources
Human Bocavirus 1 Infection of Well‐Differentiated Human Airway Epithelium [PDF]
Current Protocols in Microbiology, 2020 AbstractHuman bocavirus 1 (HBoV1) is a small DNA virus that belongs to the Bocaparvovirus genus of the Parvoviridae family. HBoV1 is a common respiratory pathogen that causes mild to life‐threatening acute respiratory tract infections in children and immunocompromised individuals, infecting both the upper and lower respiratory tracts.
Ziying, Yan +2 more
openaire +4 more sources
Primary and Secondary Human Bocavirus 1 Infections in a Family, Finland
Emerging Infectious Diseases, 2013 Human bocavirus 1 (HBoV1) was detected in a young child hospitalized for pneumonia and subsequently in his twin brother and other family members. The mother’s nasopharyngeal samples intermittently showed HBoV1 DNA; the grandmother had HBoV1 reinfection ...
Alma Jula +6 more
doaj +5 more sources
Differential seroprevalence of human bocavirus species 1-4 in Beijing, China. [PDF]
PLoS ONE, 2012 BACKGROUND: Four species of human bocaviruses (HBoV1-4) have been identified based on phylogenetic analysis since its first report in 2005. HBoV1 has been associated with respiratory disease, whereas HBoV2-4 are mainly detected in enteric infections ...
Li Guo +9 more
doaj +5 more sources
Human Bocavirus 1 Primary Infection and Shedding in Infants [PDF]
Journal of Infectious Diseases, 2015 Human bocavirus 1 (HBoV-1) is frequently detected in young children. The role of HBoV-1 in respiratory illness is unclear, owing to frequent detection in asymptomatic children.Weekly oral fluid samples from a longitudinal cohort of infants were tested by quantitative polymerase chain reaction for HBoV-1 DNA.
Emily T, Martin +4 more
openaire +3 more sources
Human Bocavirus 1 Is a Novel Helper for Adeno-associated Virus Replication [PDF]
Journal of Virology, 2017 ABSTRACT Human bocavirus 1 (HBoV1) is an autonomous parvovirus that infects well-differentiated primary human airway epithelia (HAE) in vitro . In human embryonic kidney HEK293 cells, the transfection of a duplex HBoV1 genome initiates viral DNA replication and produces progeny virions that are infectious ...
Zekun, Wang +5 more
openaire +3 more sources
Development and Validation of a Predictive Model for Wheezing Illness Following Human Bocavirus 1 Infection in Children [PDF]
MicroorganismsHuman Bocavirus 1 (HBoV1) is one major pathogen that has been associated with wheezing illnesses. However, there is still a lack of effective clinical predictive indicators for wheezing illnesses in children infected with HBoV1.
Ri De +9 more
doaj +2 more sources