Results 121 to 130 of about 6,407,977 (345)

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

HUMAN RIGHTS AND THE NON-HUMAN BLACK BODY

open access: yesSur: International Journal on Human Rights, 2018
When a black student threw faeces at a statue of British imperialist Cecil John Rhodes at the University of Cape Town in South Africa, it sparked the formation of #RhodesMustFall, a black radical student movement that sought to address systemic racism at
A. Kayum Ahmed
doaj  

Automatic Identification of Inertial Sensors on the Human Body Segments [PDF]

open access: yes, 2011
In the last few years, inertial sensors (accelerometers and gyroscopes) in combination with magnetic sensors was proven to be a suitable ambulatory alternative to traditional human motion tracking systems based on optical position measurements.
Beijnum, B.J.F. van   +2 more
core   +2 more sources

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

The Growth of the Surface Area of the Human Body. [PDF]

open access: green, 1936
Eugene F. Du Bois   +2 more
openalex   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

open access: yesMolecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez   +5 more
wiley   +1 more source

In-to-Out Body Antenna-Independent Path Loss Model for Multilayered Tissues and Heterogeneous Medium

open access: yesSensors, 2014
In this paper, we investigate multilayered lossy and heterogeneous media for wireless body area networks (WBAN) to develop a simple, fast and efficient analytical in-to-out body path loss (PL) model at 2.45 GHz and, thus, avoid time-consuming simulations.
Divya Kurup   +4 more
doaj   +1 more source

No-bodies Human Rights. An Interdisciplinary Exploration of Bodies in Human Rights

open access: yesUtrecht Law Review
One can hardly imagine human rights – aimed to guarantee minimum requirements for a dignified life for all – without human bodies. In legal thinking, however, the corporeal is often remarkably absent, or overshadowed by abstract, disembodied conceptualisations of ‘the’ human being and his (more than her, or their) presupposed autonomy.
Tigchelaar, Jet, Oude Breuil, Brenda
openaire   +2 more sources

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