Results 131 to 140 of about 14,485,412 (367)

Evaluation of Forward Fall on the Outstretched Hand Using MADYMO Human Body Model [PDF]

open access: yesarXiv, 2018
Falls and their related injuries pose a significant risk to human health. One of the most common falls, the forward fall, frequently occurs among adults and the elderly. In this study, we propose using a human body model, developed using the MAthematical DYnamic MOdel (MADYMO) software, in place of human subjects, to investigate forward fall-related ...
arxiv  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Validation of the mathematical model of upper body biomechanics using neural networks [PDF]

open access: yesBalneo and PRM Research Journal
The paper presents artificial neural networks (ANNs) as a tool for validating the mathematical model. The neural network architecture must learn the relationship between the inputs (which are the parameters of the biomechanical mathematical model, such ...
Elena Mereuta   +4 more
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

HUMAN RIGHTS AND THE NON-HUMAN BLACK BODY

open access: yesSur: International Journal on Human Rights, 2018
When a black student threw faeces at a statue of British imperialist Cecil John Rhodes at the University of Cape Town in South Africa, it sparked the formation of #RhodesMustFall, a black radical student movement that sought to address systemic racism at
A. Kayum Ahmed
doaj  

Interplay of integrins and selectins in metastasis

open access: yesMolecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva   +2 more
wiley   +1 more source

DiffBody: Human Body Restoration by Imagining with Generative Diffusion Prior [PDF]

open access: yesarXiv
Human body restoration plays a vital role in various applications related to the human body. Despite recent advances in general image restoration using generative models, their performance in human body restoration remains mediocre, often resulting in foreground and background blending, over-smoothing surface textures, missing accessories, and ...
arxiv  

No-bodies Human Rights. An Interdisciplinary Exploration of Bodies in Human Rights

open access: yesUtrecht Law Review
One can hardly imagine human rights – aimed to guarantee minimum requirements for a dignified life for all – without human bodies. In legal thinking, however, the corporeal is often remarkably absent, or overshadowed by abstract, disembodied conceptualisations of ‘the’ human being and his (more than her, or their) presupposed autonomy.
Tigchelaar, Jet, Oude Breuil, Brenda
openaire   +2 more sources

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