Results 51 to 60 of about 2,496,590 (268)

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Love songs and serenades: a theoretical review of music and romantic relationships

open access: yesFrontiers in Psychology
In this theoretical review, we examine how the roles of music in mate choice and social bonding are expressed in romantic relationships. Darwin’s Descent of Man originally proposed the idea that musicality might have evolved as a sexually selected trait.
Joshua S. Bamford   +5 more
doaj   +1 more source

The Reflection on the Originality of the Study of Physical Education, Health and Sport Sciences in Japan [PDF]

open access: yesThe Asian Journal of Kinesiology
OBJECTIVES The purpose of this study is to discuss the redefinition of the Physical Education, Health, and Sport Sciences (PEHSS) in Japan by considering its originality. METHODS The method of this study is reflective consideration in philosophy.
Koji Takahashi
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The social perception of performance enhancement and body modification: A systematic review and meta-analysis on anabolic steroids, tattoos, and cosmetic surgery

open access: yesActa Psychologica
To our knowledge, few studies have attempted to explore the social perception of targets engaged in performance enhancement and body modification, and none has done so through a systematic review and meta-analysis.
Hailemariam Weldemariam   +5 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Lectura teológica del derecho a la salud sexual. Desde la experiencia de un grupo de mujeres que vive con vih

open access: yesFranciscanum, 2017
Drama of women with HIV is called to become a theological place because God speaks through the words and deeds that occur in that place and because its liberating and saving potential for the individuals involved.
José Luis Meza Rueda
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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