Results 131 to 140 of about 10,348,104 (306)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon +11 more
wiley +1 more source
Grid-like entorhinal representation of an abstract value space during prospective decision making
Nature CommunicationsHow valuable a choice option is often changes over time, making the prediction of value changes an important challenge for decision making. Prior studies identified a cognitive map in the hippocampal-entorhinal system that encodes relationships between ...
Alexander Nitsch +4 more
doaj +1 more source
Enriching Statistical Inferences on Brain Connectivity via Latent Space Graph Embeddings
, 2020 1
Guorong Wu, Xin Ma, KIM, WON HWA
core
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Comparison of whole-brain task-modulated functional connectivity methods for fMRI task connectomics
Communications BiologyHigher brain functions require flexible integration of information across widely distributed brain regions depending on the task context. Resting-state functional magnetic resonance imaging (fMRI) has provided substantial insight into large-scale ...
Ruslan Masharipov +4 more
doaj +1 more source
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source
Brain death and death of human individual
, 2010 The revised Organ Transplant Law of Japan, enforced from July, 2010, has made "brain death", as well as "cardiac death", death of human individual and procurement of an organ from a brain dead body is now possible by a surviving family's consent ...
Machino, Saku
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan +5 more
wiley +1 more source
A reduction in self-reported confidence accompanies the recall of memories distorted by prototypes
Communications PsychologyWhen we recall a past event, we reconstruct the event based on a combination of episodic details and semantic knowledge (e.g., prototypes). Though prototypes can impair the veracity of recall, it remains unclear whether we are metacognitively aware of ...
Casper Kerrén +2 more
doaj +1 more source
Emigration Prospects and Human Capital in the Developing Countries: The Possibility of the Qualitative Brain Gain [PDF]
In this paper we study the net effect of high-skilled emigration. Hence, we elaborate a simple theoretical model that studies the net effect of high-skilled emigration. The result showed that the emigration in the case where the fraction of human capital
Kouni, Mohamed
core