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Differential Effects of Snail-KO in Human Breast Epithelial Cells and Human Breast Epithelial × Human Breast Cancer Hybrids [PDF]

open access: yesInt J Mol Sci
Snail and Zeb1 have been suggested as markers for the hybrid/mixed epithelial (E)/mesenchymal (M) state of cancer cells. Such cancer cells co-express E- and M-specific transcripts and possess cancer stem cell properties. M13HS-2/-8 tumor hybrid clones derived from human M13SV1-EGFP-Neo breast epithelial cells and human HS578T-Hyg breast cancer cells ...
Silvia Keil, Thomas Dittmar
europepmc   +3 more sources

A comparative metabolomics analysis of domestic yak (Bos grunniens) milk with human breast milk

open access: yesFrontiers in Veterinary Science, 2023
Yaks are tough animals living in Tibet’s hypoxic stress environment. However, the metabolite composition of yak milk and its role in hypoxic stress tolerance remains largely unexplored.
Wenhao Li   +10 more
doaj   +1 more source

Possible correlation of apical localization of MUC1 glycoprotein with luminal A-like status of breast cancer

open access: yesScientific Reports, 2023
Adjuvant chemotherapy has played a major role in the treatment of hormone receptor-positive breast cancer for many years. To better determine which patient subsets need adjuvant chemotherapy, various gene expression analyses have been developed, but cost-
Ryoko Semba   +14 more
doaj   +1 more source

caAtlas: An immunopeptidome atlas of human cancer

open access: yesiScience, 2021
Summary: Comprehensive characterization of tumor antigens is essential for the design of cancer immunotherapies, and mass spectrometry (MS)-based immunopeptidomics enables high-throughput identification of major histocompatibility complex (MHC)-bound ...
Xinpei Yi   +6 more
doaj   +1 more source

Acute myocarditis during adjuvant therapies for breast cancer: a case report

open access: yesSurgical Case Reports, 2023
Background With the improvement of optimal perioperative drug therapy for breast cancer patients, physicians now have to treat the adverse effects and comorbidities associated with long-term treatments. We report a case who suffered cardiac arrest due to
Yumiko Ushiyama   +8 more
doaj   +1 more source

IgG4-related mastitis characterized by skin thickening of the breast: a case report

open access: yesSurgical Case Reports, 2023
Background IgG4-related diseases are characterized by marked infiltration and IgG4-positive plasma cells and fibrosis, and involve multiple organs. However, IgG4-related mastitis is rare. We report a case of mastitis associated with IgG4-related disease.
Moe Itakura   +7 more
doaj   +1 more source

Microbiota of Human Breast Tissue [PDF]

open access: yesApplied and Environmental Microbiology, 2014
ABSTRACT In recent years, a greater appreciation for the microbes inhabiting human body sites has emerged. In the female mammary gland, milk has been shown to contain bacterial species, ostensibly reaching the ducts from the skin. We decided to investigate whether there is a microbiome within the mammary tissue.
Urbaniak, Camilla   +11 more
openaire   +4 more sources

Clinicopathological Features Related to the Efficacy of CDK4/6 Inhibitor-Based Treatments in Metastatic Breast Cancer

open access: yesBreast Cancer: Basic and Clinical Research, 2022
Background: Resistance to endocrine therapy has been a major obstacle in the management of hormone receptor (HR)-positive metastatic breast cancer (MBC).
Ayana Shikanai   +6 more
doaj   +1 more source

Immunologically “cold” triple negative breast cancers engraft at a higher rate in patient derived xenografts

open access: yesnpj Breast Cancer, 2022
TNBC is a heterogeneous subtype of breast cancer, and only a subset of TNBC can be established as PDXs. Here, we show that there is an engraftment bias toward TNBC with low levels of immune cell infiltration.
Varduhi Petrosyan   +8 more
doaj   +1 more source

Primary breast non-Hodgkin’s lymphoma in a 14-year-old girl: a case report

open access: yesSurgical Case Reports, 2020
Background Primary breast lymphoma is rare. Occurrence rates of malignant breast tumors in children are also quite low. We herein report a B-lymphoblastic lymphoma of the breast arisen in an adolescent girl.
Yumiko Ishizuka   +7 more
doaj   +1 more source

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