Results 11 to 20 of about 801,707 (316)

Metastatic breast tumors from extramammary malignancies: a case series

Surgical Case Reports, 2021
Background Metastatic breast tumors from extramammary malignancies are quite rare. Characteristics of such tumors are unclear due to small number of reported cases.
Ryoko Semba, Yoshiya Horimoto, Atsushi Arakawa, Mitsue Saito   +3 more
doaj   +1 more source

Comparison of tumors with HER2 overexpression versus HER2 amplification in HER2-positive breast cancer patients

BMC Cancer, 2022
Background Human epidermal growth factor receptor 2 (HER2)-positive tumors are defined by protein overexpression (3+) or gene amplification using immunohistochemistry (IHC) or fluorescence in situ hybridization (FISH), respectively.
Yoshiya Horimoto, Yumiko Ishizuka, Yuko Ueki, Toru Higuchi, Atsushi Arakawa, Mitsue Saito   +5 more
doaj   +1 more source

Clinicopathological Examination of Metaplastic Spindle Cell Carcinoma of the Breast: Case Series

Breast Cancer: Basic and Clinical Research, 2021
Background: Spindle cell carcinoma (SpCC) of the breast is a rare histological type, a subtype of metaplastic carcinoma characterized by atypical spindle cell and epithelial carcinoma.
Yumiko Ishizuka, Yoshiya Horimoto, Naotake Yanagisawa, Atsushi Arakawa, Katsuya Nakai, Mitsue Saito   +5 more
doaj   +1 more source

Cells of human breast milk [PDF]

Cellular & Molecular Biology Letters, 2017
Human milk is a complex fluid that has developed to satisfy the nutritional requirements of infants. In addition to proteins, lipids, carbohydrates and other biologically active components, breast milk contains a diverse microbiome that is presumed to colonize the infant gastrointestinal tract and a heterogeneous population of cells with unclear ...
Malgorzata Witkowska-Zimny, Ewa Kaminska-El-Hassan   +1 more
openaire   +3 more sources

A comprehensive genomic and transcriptomic dataset of triple-negative breast cancers

Scientific Data, 2022
Measurement(s) RNA expression profiling • whole-exome sequencing (WES) • somatic mutations • copy number alterations (CNAs) Technology Type(s) RNA sequencing • DNA sequencing • OncoScan CNV assay Factor Type(s) Intervention or procedure Sample ...
Qingwang Chen, Yaqing Liu, Yuechen Gao, Ruolan Zhang, Wanwan Hou, Zehui Cao, Yi-Zhou Jiang, Yuanting Zheng, Leming Shi, Ding Ma, Jingcheng Yang, Zhi-Ming Shao, Ying Yu   +12 more
doaj   +1 more source

Adaptive immune signature in HER2-positive breast cancer in NCCTG (Alliance) N9831 and NeoALTTO trials

npj Breast Cancer, 2022
Trastuzumab acts in part through the adaptive immune system. Previous studies showed that enrichment of immune-related gene expression was associated with improved outcomes in HER2-positive (HER2+) breast cancer. However, the role of the immune system in
Saranya Chumsri, Zhuo Li, Daniel J. Serie, Nadine Norton, Afshin Mashadi-Hossein, Kathleen Tenner, Heather Ann Brauer, Sarah Warren, Patrick Danaher, Gerardo Colon-Otero, Ann H. Partridge, Lisa A. Carey, Florentine Hilbers, Veerle Van Dooren, Eileen Holmes, Serena Di Cosimo, Olena Werner, Jens Bodo Huober, Amylou C. Dueck, Christos Sotiriou, Cristina Saura, Alvaro Moreno-Aspitia, Keith L. Knutson, Edith A. Perez, E. Aubrey Thompson   +24 more
doaj   +1 more source

Cerebral hemorrhage due to amyloid angiopathy that was difficult to differentiate from breast cancer metastasis: a case report

Surgical Case Reports, 2021
Background Breast cancer patients are known to develop brain metastasis at a relatively high frequency. However, imaging findings of brain metastases vary, and it is sometimes very difficult to distinguish these from other tumorous lesions and non ...
Toshitaka Uomori, Yoshiya Horimoto, Masashi Takanashi, Ayana Shikanai, Katsuya Nakai, Astushi Arakawa, Mitsue Saito   +6 more
doaj   +1 more source

Effects of tumor-infiltrating lymphocytes on nonresponse rate of neoadjuvant chemotherapy in patients with invasive breast cancer

Scientific Reports, 2023
High level of tumor-infiltrating lymphocytes (TILs) can predict the rate of total pathological complete remission (tpCR) of breast cancer patients who receive neoadjuvant chemotherapy (NACT).
Xiao-Long Qian, Xiao-Qing Xia, Ya-Qing Li, Yu-Mian Jia, Yuan-Yuan Sun, Yuan-Ming Song, Hui-Qin Xue, Yan-Fei Hao, Jin Wang, Xiao-Zi Wang, Chen-Ying Liu, Xin-Min Zhang, Li-Na Zhang, Xiao-Jing Guo   +13 more
doaj   +1 more source

TG2 as a novel breast cancer prognostic marker promotes cell proliferation and glycolysis by activating the MEK/ERK/LDH pathway

BMC Cancer, 2022
Background Breast cancer (BC) is the most common malignant tumor among women worldwide. Tissue transglutaminase 2 (TG2) has been reported as a major player across several types of cancer.
Dahai Xu, Ning Xu, Liang Sun, Zhaoying Yang, Miao He, Youjun Li   +5 more
doaj   +1 more source

Ring finger protein 126 promotes breast cancer metastasis and serves as a potential target to improve the therapeutic sensitivity of ATR inhibitors

Breast Cancer Research, 2022
Background/aims This study explores the relationship between the E3 ubiquitin ligase Ring finger protein 126 (RNF126) and early breast cancer metastasis and tests the hypothesis that RNF126 determines the efficacy of inhibitors targeting Ataxia ...
You Pan, Yuchao Yang, Rong Huang, Huawei Yang, Qinghua Huang, Yinan Ji, Jingxing Dai, Kun Qiao, Wei Tang, Longgui Xie, Ming Yin, Jun Ouyang, Shipeng Ning, Danke Su   +13 more
doaj   +1 more source