Results 21 to 30 of about 801,707 (316)
Abstract Given the very high incidence of breast pathology and the costs—both human and financial—that are incurred as a result of breast abnormalities, a complete, accurate, and cogent stand-alone presentation is a necessary tool that can be of great use to many health science students and instructors.
Douglas Gould +2 more
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Splice isoform switching regulated by the heterogeneous nuclear ribonucleoprotein M (hnRNPM) induces EMT and metastasis. Here, the authors report that AKAP8 is a metastasis suppressor that inhibits the splicing activity of hnRNPM and antagonizes genome ...
Xiaohui Hu +8 more
doaj +1 more source
Background Rating lymphocytes (TILs) are a prognostic marker in breast cancer and high TIL infiltration correlates with better patient outcomes. Meanwhile, parameters involving immune cells in peripheral blood have also been established as prognostic ...
Hiroko Onagi +15 more
doaj +1 more source
Chinese breast cancer patients have not been well represented in clinical sequencing studies. Here the authors analyse the mutational landscape of 1,134 Chinese breast cancer patients, finding actionable targets and a higher prevalence of p53 and Hippo ...
Guan-Tian Lang +27 more
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Development of the Human Breast [PDF]
Mammalia are so named based on the presence of the mammary gland in the breast. The mammary gland is an epidermal appendage, derived from the apocrine glands. The human breast consists of the parenchyma and stroma, originating from ectodermal and mesodermal elements, respectively. Development of the human breast is distinctive for several reasons.
Asma, Javed, Aida, Lteif
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Proteolysis in human breast cancer [PDF]
The process of proteolysis is important at several stages of the metastatic cascade. A balance between the expression of the genes encoding endogenous proteinases and inhibitors exists and when the production of proteinases exceeds that of inhibitors proteolysis occurs.To determine whether differences in the profile and activity of proteinases and ...
E A, Garbett +3 more
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HUMAN MICROBIOTA AND BREAST CANCER
Breast cancer is the leading malignancy in women worldwide. To date, much is known about the molecular subtypes of these malignant neoplasms and the mechanisms of drug resistance. Significant success has been achieved in approaches to early diagnosis, which allows identifying the tumor process in the early stages of development.
Yu V, Shvets, O O, Lykhova, V F, Chekhun
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The recurrence of non-metastatic endometrial carcinoma (EC) (6 to 21%) might be due to disseminated tumor cells. This feasibility study investigated whether circulating tumor cells (CTCs) were detectable in blood samples from the peripheral and ovarian ...
Sarah Francini +8 more
doaj +1 more source
Aquaglyceroporins in Human Breast Cancer
Aquaporins are water channels that facilitate passive water transport across cellular membranes following an osmotic gradient and are essential in the regulation of body water homeostasis. Several aquaporins are overexpressed in breast cancer, and AQP1, AQP3 and AQP5 have been linked to spread to lymph nodes and poor prognosis.
Teresa Kirkegaard +3 more
openaire +4 more sources
Male breast hypertrophy - a review of modern methods of treatment
Gynecomastia is a benign enlargement of the mammary gland in males. Nowadays it is a common disorder of all ages, including newborns, adolescents and adults. It may be bilateral or unilateral enlargement of the breast.
Rafal Wojcik +6 more
doaj +3 more sources

