Results 141 to 150 of about 9,417,149 (359)

The mediating role of neuroticism and anxiety sensitivity in the relationship between childhood trauma and panic disorder severity

open access: yesFrontiers in Psychiatry
ObjectiveDespite advancements in understanding panic disorder (PD), its etiology and pathogenesis remain elusive, particularly concerning the influence of psychosocial factors.
Fang He   +11 more
doaj   +1 more source

Engineered Foxp1high Exosomes Ameliorates Systemic Lupus Erythematosus

open access: yesAdvanced Science, EarlyView.
This study presents a dual‐engineering strategy combining mesenchymal stem cell aggregation and Foxp1 overexpression to generate Foxp1high aggregation exosomes with enhanced immunomodulatory properties. These engineered exosomes exhibit immune organ targeting and superior efficacy in systemic lupus erythematosus treatment by promoting Treg ...
Luhan Niu   +9 more
wiley   +1 more source

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

open access: yesAdvanced Science, EarlyView.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao   +17 more
wiley   +1 more source

Human capital and entrepreneurial performance: the mediating effect of entrepreneurial innovation in Indonesia

open access: yesCogent Social Sciences
Micro, Small, and Medium Enterprises (MSMEs) are pivotal to Indonesia’s economy, offering vast employment and significantly contributing to economic growth.
Anissa Lestari Kadiyono, Hery Susanto
doaj   +1 more source

Heterointerface‐Modulated Synthetic Synapses Exhibiting Complex Multiscale Plasticity

open access: yesAdvanced Science, EarlyView.
An asymmetric dual‐gate heterointerface‐regulated artificial synapse (HRAS) is developed, employing distinct ion concentrations and dielectric coupling to form precise dual‐interface channels. Through lateral modulation, HRAS realizes, for the first time, the intricate interplay of lateral inhibition/enhancement and multi‐level short‐ and long‐term ...
Xingji Liu   +14 more
wiley   +1 more source

Recent Advances in mRNA Delivery Systems for Cancer Therapy

open access: yesAdvanced Science, EarlyView.
This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang   +9 more
wiley   +1 more source

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