Results 171 to 180 of about 3,157,420 (313)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

PHYSICAL AND HUMAN CAPITAL INVESTMENT: RELATIVE SUBSTITUTES IN THE ENDOGENOUS GROWTH PROCESS [PDF]

open access: yes
This paper aims at studying the interaction between growth of real output and human capital accumulation when education requires investment of physical resources.
Jorge Durán, Alexandra Rillaers
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Characteristics Associated with Infant Feeding with Both Breast Milk and Formula Milk. [PDF]

open access: yesNutrients
Watakabe K   +10 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Transmission potential of Andes virus from human to human. [PDF]

open access: yesNew Microbes New Infect
Nishiura H, Amemiya Y.
europepmc   +1 more source

Human disturbance, habitat characteristics and social environment generate sex-specific responses in vigilance of Mediterranean mouflon (Ovis gmelini musimon × Ovis sp.)

open access: yes, 2012
Vigilance is an important part of decision making process in ungulates related to risk effects. Thus, understanding the mechanisms shaping vigilance behavior provides an insight on factors influencing fitness variation between individuals.
Benoist, Stephanie - Yves
core  

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