Results 151 to 160 of about 1,772,181 (298)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Editorial: Technological advances in psychiatric treatments: a focused exploration of human-computer interaction and human factors in digital therapeutics. [PDF]
Front PsychiatryRidout S, Abd-Alrazaq A, Dhou K.
europepmc +1 more source
Using ChatGPT for human-computer interaction research: a primer. [PDF]
R Soc Open Sci, 2023 Tabone W, de Winter J.
europepmc +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
HRV-Based Multimodal Physiological Signal Monitoring Using Wearable Biosensors in Human-Computer Interaction: Cognitive Load in Real-Time Strategy Games. [PDF]
Sensors (Basel)Shi Y, Kuerban M, Jin Y, Wang C, Chen L.
europepmc +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Quantifying surface contamination in a primary care clinic using 3D gestural human-computer interaction. [PDF]
J Infect PrevDowers KH, Jurewicz KA.
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Open science practices among early-career human-computer interaction researchers in the US. [PDF]
PLoS OneChakravorti T, Gautam S, Rajtmajer S.
europepmc +1 more source