Results 61 to 70 of about 2,052,360 (329)

From the Theory of the African Origin of Humankind to Modern Social, Legal and Technological Innovations: a Brief Analytical Excursion into Anthroposociogenesis

Journal of Digital Technologies and Law
Objective: to trace the evolution of humanity and to identify the role of various social institutions in order to understand the existential role of laws aimed at ensuring the coexistence of society in the context of technological innovations.Methods ...
D. Traore
doaj   +1 more source

O REGRESSO DO DESENVOLVIMENTO HUMANO: um sintoma da pandemia de Covid-19?

Revista de Políticas Públicas, 2021
The article aims to problematize the perspective of human development whose risk of regression is pointed out as a consequence of the pandemic period triggered by COVID-19.
Carla Alessandra da Silva Nunes
doaj   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

DIMENSI AKSIOLOGIS FILSAFAT HIDUP PIIL PESENGGIRI DAN RELEVANSINYA TERHADAP PENGEMBANGAN KEBUDAYAAN DAERAH LAMPUNG

Jurnal Filsafat, 2016
The way of life of Lampung people, Piil Pesenggiri, essentially is related to existence of human being correlating to God, other human, and nature.
Himyari Yusuf
doaj   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source

An Attempt to Elucidate the Relationship Between Biological and Cultural Factors in Philosophy

Studia Philosophiae Christianae
Today, we observe disturbing phenomena accompanying technical civilization’s dynamic development. While noticing the great benefits and achievements of civilizational development, we also experience the challenges and difficulties that humanity and our ...
Ryszard F. Sadowski
doaj   +1 more source

Sam Ratulangi's philosophical cultural ideas and their implications in the principle of just and civilized humanity

Jurnal Civics: Media Kajian Kewarganegaraan, 2022
The article aims to explore the philosophical thinking of Si Tou Timou Tumou Tou (living human to humanize others) concerning the noble values contained in the second principle of the Pancasila, "Just and Civilized Humanity." The background of this paper
Theodorus Pangalila, Ambrosius Markus Loho, Tasente Tanase   +2 more
doaj   +1 more source

The practices of apartheid as a war crime: a critical analysis [PDF]

, 2014
The human suffering caused by the political ideology of apartheid in South Africa during the Apartheid era (1948-1994) prompted worldwide condemnation and a variety of diplomatic and legal responses.
A Bultz, A Cassese, A Cassese, A Guelke, A Zahar, B White, C Hall, C Kreß, C Tomuschat, C Tomuschat, D Robinson, E Wilmshurst, G Draper, G Fitzmaurice, G Solis, H Hannum, H Levie, H-P Gasser, J Bellinger, J Carter, J Dugard, J Dugard, J Gebhard, J Reynolds, J-M Henckaerts, J-M Henckaerts, J-M Henckaerts, J-M Henckaerts, K Ambos, K Dörmann, K Dörmann, K Gallant, M Kotzur, M Matheson, M Plessis Du, N Lerner, P Eden, R Clark, R Cryer, R Cryer, R Falk, R Higgins, R Jennings, S Dubow, T McCormack, T McCormack, T McCormack, U Davis, V Morris, W Schabas, Y Dinstein, Y Dinstein, Y Sandoz, Y Zilbershats   +53 more
core   +1 more source

Framing the Psycho-Social and Cultural Aspects of Human-Machine Communication

Human-Machine Communication, 2022
In this introduction to the fourth volume of the journal Human-Machine Communication, we present and discuss the nine articles selected for inclusion. In this essay, we aim to frame some crucial psychological, sociological, and cultural aspects of this ...
L. Fortunati, Autumn P. Edwards
semanticscholar   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source