Results 81 to 90 of about 597,824 (308)

Human Rights, Human Needs, Human Development, Human Security: elations ships between Four International ‘Human’ Discourses

Forum for Development Studies, 2007
Human rights, human development and human security form increasinglyimportant, partly interconnected, partly competitive and misunderstood ethicaland policy discourses. Each tries to humanize a pre-existing and unavoidablemajor discourse of everyday life, policy and politics; each has emerged withinthe United Nations world; each relies implicitly on a ...
openaire   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Evolution, Evil, Co-Creation and the Value of the World

Religions
This article builds on and supplements an earlier one in this journal about theodicy. It focuses on species extinctions and on the possible role of humanity as fallible co-creators.
Robin Attfield
doaj   +1 more source

The Catholic Doctrine of ‘Integral Human Development’ and its Influence on the International Development Community (abstract)

Revue Internationale de Politique de Développement, 2013
In 1967, Pope Paul VI posited the notion of ‘integral human development’, which, as developed by his successors, John Paul II and Benedict XVI, broke with the modern project of purely economic and technological development, resulting in an original ...
Ludovic Bertina
doaj   +1 more source

Human Psychology for Human Development

, 2022
In the sphere of social sciences, psychology is a vital subject. The development of social and humanitarian themes is rapidly rising in modern society. As a result, it is critical to engage the public in a discussion regarding the value of social sciences and related subjects. The fundamental goal of this research is to identify the human psychological
openaire   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Діалектика всезагального й особливого – сутнісний вимір культури (Dialectics of universal and peculiar-essential culture dimention) [PDF]

, 2014
Розглядається діалектика сталого і змінного в культурі як відображення закономірностей формування, розвитку і зміни ціннісних уявлень про світ та буття людини в ньому; простежується своєрідність національних образів культури в їх сутнісній ...
Мовчан, В. ( V. Movchan)
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source