Results 91 to 100 of about 597,824 (308)
Maqasid Al-Syari'ah Transformation in Law Implementation for Humanity
International Journal Ihya' 'Ulum al-DinThe needs of humanity, which is the goal of the Shari'a, never end. Maqasid Syari'ah, an approach to Islamic studies, is a benchmark in answering society's problems.
Tarmizi Tahir, Syeikh Hasan Abdel Hamid
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Zero-Sum Power Politics vs. Synergetic Politics for Human Security
Cadmus, 2023 Zero-sum power politics is a fundamental threat to human security. Synergetic relations among nations are proposed to improve human security. Among existential threats to humanity, the most immediate and little understood is the development of Artificial
Jerome C. Glenn
doaj
Protogeometer: Falling Into Future [PDF]
, 2014 Universe silence … Why? TechnoSfera … Where does it move? BioSfera … Where is the ―non-return point? NooSfera … What to do? The deep mind looks for primordial senses of the ―LifeWorld(LebensWelt).
Rogozhin, Vladimir
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Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Think Happy Thoughts : Peter Pan as a Tragic Hero
, 2014 Using Aristotle\u27s definition of the tragic hero, this work will explore J.M. Barrie\u27s novel, Peter and Wendy, and how Peter is a tragic figure.
Connelly, Sarah M.
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Civilians in the Line of Fire in the Light of Catholic Social Teaching [PDF]
, 2015 In our world today, afflicted by wars between States, by conflict between groups within States, and by the scourge of terrorism, civilians constitute the ‘vast majority of casualties in situations of armed conflict’ (UN Security Council, Resolution ...
Michael, Biju
core +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
A Cosmopolitan response to the 'war on terror' [PDF]
, 2019 This article explores the relevance and the significance of cosmopolitanism as an approach to understanding the ‘war on terror’. The article details how cosmopolitanism affords a perspective through which it is possible to critique and deconstruct the ...
Ahmed, S., Ahmed, S.
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