Results 111 to 120 of about 25,111,230 (304)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Improving the Measurement of Human Development [PDF]

open access: yes
We propose a new Human Development Index that involves a number of changes with respect to the present one, even though it keeps the basic structure of the index (namely, preserving “health”, “education” and “material wellbeing” as the three basic ...
Antonio Villar   +2 more
core  

Integration of Maqashid Sharia and Human Development: Case Study in Indonesia

open access: yesIndonesian Interdisciplinary Journal of Sharia Economics
This study investigates the connection between Maqashid Syariah principles and the Human Development Index (HDI) across 34 Indonesian provinces from 2019 to 2023.
Geraldi Fikri Putra Pradita   +1 more
doaj   +1 more source

Territorial Differences of Human Development Index in Romania [PDF]

open access: yesRomanian Review of Regional Studies, 2011
The measuring of human capital, human development from both a quantitative and a qualitative point of view is difficult, the problem being further complicated if we consider regional and territorial approaches as well.
IBOLYA KURKÓ
doaj  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

The Spatial Dimension of Human Development Index in Indonesia [PDF]

open access: yes
As the new paradigm of economic development pioneered by UNDP and Mahbub Ul-Haq undertaken, development processes no longer viewed as monodimensional process of economic growth indicated by GDP growth solely.
Rullan Rinaldi, Eva Nurwita
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Optimizing the new formulation of the United Nations' human development index: An empirical view from data envelopment analysis. [PDF]

open access: yes
In this paper, we propose a new way to simulate an optimal Human Development Index [HDI]. Indeed, the formulation of the original HDI established by the United Nations Development Programme [UNDP] relies on a major methodological shortcoming, namely the ...
Stéphane Blancard   +1 more
core  

Multiple Regression Analysis of Indicators that Determine Competitiveness [PDF]

open access: yesOvidius University Annals: Economic Sciences Series
The correlation between Human Development Index (HDI), Sustainable Development Goals Index (SDG) and Competitiveness Index (CI) reflects how countries balance social progress, environmental sustainability and economic performance.
Raluca Podaşcă
doaj  

Home - About - Disclaimer - Privacy