Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Does club convergence matter? Empirical evidence on inequality in the human development index among Indian states. [PDF]
Nag A, Pradhan J.
europepmc +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Favorable cervical cancer mortality-to-incidence ratios of countries with good human development index rankings and high health expenditures. [PDF]
Shen TT, Long CY, Wu MP.
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Poset sensitivity analysis reveals post 2020 changes in human development index components. [PDF]
Martori F, Hirai T.
europepmc +1 more source
The relationship between maternal death due to COVID-19 and the human development index in East Java, Indonesia. [PDF]
Prasetyo B +7 more
europepmc +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Investigation of Human Development Index in Sistan & Balouchestan Province (1989-2000) [PDF]
mohamad hosein kareimkoshteh +1 more
doaj +1 more source
Breast cancer in reproductive-age women in Croatia: trends, demographic shifts, and correlation with human development index. [PDF]
Balorda L +3 more
europepmc +1 more source

