Results 151 to 160 of about 1,193,129 (257)

Trends and patterns of global health risk factors (2015-2019): a composite index approach across 100 countries stratified by human development index groups. [PDF]

J Health Popul Nutr
Junaid KP, Kiran T, Gupta M, Kishore K, Siwatch S.   +4 more
europepmc   +1 more source

Beliefs and Barriers to COVID-19 Vaccine Acceptance in Three Countries with Different Human Development Index (HDI) Scores: A Comparative Study. [PDF]

Patient Prefer Adherence, 2022
Makki S, Siddiqua A, Wahab S, Siddiqui S, Faheemuddin M, Abobaker I, Abdelmoniem A, Khaled A.   +7 more
europepmc   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Vaccination Coverage Against Coronavirus Disease 2019 in People Living on Quilombos in Brazil and Its Association With the Human Development Index and the Quality of the Health System. [PDF]

J Med Virol
Costa PT, Mello LS, Marques LFA, Dos Santos VS, Marson FAL.   +4 more
europepmc   +1 more source

Correlation between human development index and its components with COVID-19 indices: a global level ecologic study. [PDF]

BMC Public Health, 2022
Mirahmadizadeh A, Ghelichi-Ghojogh M, Vali M, Jokari K, Ghaem H, Hemmati A, Jafari F, Dehghani SS, Hassani AH, Jafari A, Rezaei F.   +10 more
europepmc   +1 more source

Structure and the Human Development Index

, 2019
This paper provides an alternative way of measuring human development that takes explicitly into account the differences in the countries’ population structures. The interest of this proposal stems from two complementary elements. First, that there is an enormous diversity in the population structures of those countries analysed in the Human ...
Herrero, Carmen, Martínez Rico, Ricardo, Villar, Antonio   +2 more
openaire   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

The COVID-19 health emergency: the influence of the Human Development Index on the reorganization of primary care. [PDF]

Front Public Health
Corrêa APV, Ribeiro AC, Cano RDN, Magno GD, Álvarez-Nieto C, Uehara SCDSA.   +5 more
europepmc   +1 more source

Lip and Oral Cavity Cancer Incidence and Mortality Rates Associated with Smoking and Chewing Tobacco Use and the Human Development Index in 172 Countries Worldwide: An Ecological Study 2019-2020. [PDF]

Healthcare (Basel), 2023
Hernández-Morales A, González-López BS, Scougall-Vilchis RJ, Bermeo-Escalona JR, Velázquez-Enríquez U, Islas-Zarazúa R, Márquez-Rodríguez S, Sosa-Velasco TA, Medina-Solís CE, Maupomé G.   +9 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source