Results 241 to 250 of about 3,317,170 (346)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Pattern of burden cancer breast and relationshipin to human development index in Iran 2009 to 2019: an observational study based on the Global Burden of Diseases. [PDF]

BMC Womens Health
Shoorabeh FF, Goodarzi E, Shafeai F, Pordanjani SR, Abbasi M.   +4 more
europepmc   +1 more source

Human development index of Ukraine

, 2016
Human Development Index (HDI) includes 3 basic aspects of human development: health, knowledge, a decent standard of living. A country scores higher HDI when the lifespan is higher, the education level and the GDP per capita is higher, the fertility and inflation rates are lower.
openaire   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Perinatal health outcomes of offspring of internal migrant women according to human development index: a registry-based cohort study of over 10 million live births from Brazil. [PDF]

Lancet Reg Health Am
Cerqueira-Silva T, Paixao ES, Falcao IR, Guimarães JMN, Rodrigues LC, Baribieri A, Ababukar I, Barreto ML, Pescarini JM.   +8 more
europepmc   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Science growth and human development index in Iran

Journal of Research in Medical Sciences, 2015
Ahmad Fayaz-Bakhsh, Arefeh Mousavi
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Determinants of the Human Development Index in Pakpak Bharat Regency, Indonesia

Nurhalimah Boangmanalu, Nurlina Nurlina, Asnidar Asnidar   +2 more
openalex   +1 more source

IMPLEMENTATION POLICIES ENHANCING HUMAN DEVELOPMENT INDEX IN THE DISTRICT PANDEGLANG PROVINCE BANTEN

, 2017
Tauficurokhman Tauficurokhman
openalex   +2 more sources