A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Human disturbance alters the foraging and spatiotemporal activity of a large carnivore. [PDF]
Barceló G +3 more
europepmc +1 more source
Goitered Gazelle Gazella subgutturosa Responded to Human Disturbance by Increasing Vigilance Rather than Changing the Group Size. [PDF]
Xu W +6 more
europepmc +1 more source
Associations of Sleep and Shift Work With Osteoarthritis Risk
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships among circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000–person cohort, we evaluated associations among sleep duration, sleeplessness/insomnia, and shift
Elizabeth L. Yanik +5 more
wiley +1 more source
Carbon pathways and trophic attributes are conserved in carnivorous reef fishes across a major human disturbance gradient. [PDF]
Ramirez MD +4 more
europepmc +1 more source
Human Disturbance Increases Health Risks to Golden Snub-Nosed Monkeys and the Transfer Risk of Pathogenic Antibiotic-Resistant Bacteria from Golden Snub-Nosed Monkeys to Humans. [PDF]
Zou S +5 more
europepmc +1 more source
The Human Gut Microbiota in all its States: From Disturbance to Resilience
Julien Tap +2 more
openalex +2 more sources
New Onset of Fibromyalgia After Exposure to a Combat Environment: A Longitudinal Cohort Study
Objective Traumatic life events are hypothesized to be triggers for the onset of fibromyalgia. Posttraumatic stress disorder (PTSD) is a common comorbidity of fibromyalgia. However, limited prospective data are available on the development of fibromyalgia after exposure to high‐magnitude stress.
Jay B. Higgs +15 more
wiley +1 more source
Impacts of Land Use and Water Quality on Macroinvertebrate Diversity Under Human Disturbance in the Lake Chaohu Basin, China. [PDF]
Chen B, Ji Q, Yao Y, Zhang Z, Lin Y.
europepmc +1 more source
Association of human disturbance and gastrointestinal parasite infection of yellow baboons in western Tanzania. [PDF]
Mason B +5 more
europepmc +1 more source

