Results 61 to 70 of about 7,975,927 (282)
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
BACKGROUND: Disturbance was a performance at Koppenplatz, Mitte, Berlin on 17 September 2017, directed and scripted by Paul Carter. Involving 25 participants over 30 minutes, it responded to Karl Biedermann and Eva Butzmann's 1989/1996 Kristallnacht ...
Paul Carter (18030292)
core +1 more source
NON-LINEAR OBSERVER-BASED CONTROL OF FLEXIBLE-JOINT MANIPULATORS USED IN MACHINE PROCESSING [PDF]
Lien vers la version éditeur: http://proceedings.asmedigitalcollection.asme.org/proceeding.aspx?articleid=1727347&resultClick=3This paper proposes to use a non-linear observer to build the state and the external force of flexible manipulator robots ...
ABBA, Gabriel +5 more
core +1 more source
Urban Flora Biodiversity of Some Continental Cities of the Po Plain (Emilia-Romagna, Northern Italy)
Urban flora is a more and more interesting research subject, in light of the ongoing environmental change and biological homogenisation, since urban contexts are much more diversified that natural ones and, therefore, they offer much more colonisation ...
Alessandro Alessandrini +7 more
doaj +1 more source
Human Dimensions of Forest Disturbance by Insects: An International Synthesis [PDF]
Ecological disturbances of forests by insects have a complex array of associated human dimensions presenting complications for natural resource decision making and relationships between stakeholders and managers. This paper discusses the human context of forest disturbances by insects by reviewing four cases of bark beetle forest disturbance from ...
Flint, Courtney G. +2 more
openaire +3 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Rapid development and climate change in southeast Asia is placing unprecedented pressures on freshwater ecosystems, but long term records of the ecological consequences are rare.
Charlotte L. Briddon +9 more
doaj +1 more source
We studied beavers’ dietary preferences and the role of several factors (such as plant species, size and anthropopression level) that affect the beavers’ foraging in northern Poland.
Mateusz Jackowiak +2 more
doaj +1 more source
Human Disturbance of Karst Environments
Karst environments have been impacted by human activity for thousands of years, ever since people started living in caves for shelter, needing building supplies and water. As human population has increased, so has its disturbance of the karst landscape.
van Beynen, Philip E., van Beynen, Kaya
openaire +2 more sources

