Results 71 to 80 of about 7,975,927 (282)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Effects of Varied Stimuli on Escape Behavior Diversification of Himalayan Marmots for Different Human Disturbances

open access: yesAnimals
We measured the alert distance (AD), flight-initiation distance (FID), buffer distance (BD), and distance fled (DF) of Himalayan marmots (Marmota himalayana) from four populations experiencing human disturbances of the same persistence but different ...
Tao Lei   +6 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

California's Endangered Belding’s Savannah Sparrow (Passerculus sandwichensis beldingi): Tolerance of Pedestrian Disturbance

open access: yesAvian Conservation and Ecology, 2009
Salt marshes constitute habitat islands for many endemic animal species, particularly along the California coast, where urban sprawl has fragmented this habitat.
Esteban Fernández-Juricic, Eric F Zahn
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

The impact of disturbance from photographers on the Blue-crowned Laughingthrush (Garrulax courtoisi)

open access: yesAvian Conservation and Ecology, 2017
Human disturbance may cause significant declines in animal populations. The Blue-crowned Laughingthrush (Garrulax courtoisi) is critically endangered and restricted to a small area in Wuyuan, Jiangxi Province, China. Disturbance from photographers in the
Weiwei Zhang   +3 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Chinese Pangolins in China Demonstrate Regional Differences in Burrow Habitat Selection

open access: yesAnimals
Knowledge of the habitat characteristics of endangered species is an important basis for in situ conservation, release-site selection, and habitat modification.
Dongling Liang   +5 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Behavioural responses of Bonelli's eagles to human disturbances: Assessing the effect on reproduction and suggested mitigating measures

open access: yesPeople and Nature
There has been increasing recognition of the adverse effects of outdoor recreation on the behavioural ecology, breeding success and ultimate abandonment of territories in several raptor species, such as the Bonelli's Eagle (Aquila fasciata).
José E. Martínez   +5 more
doaj   +1 more source

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