Results 91 to 100 of about 7,975,927 (282)

Reconstructing Long-Term Annual Aboveground Carbon Trajectories in Urban Mangroves Using Satellite-Informed Species Composition and Canopy Height

Remote Sensing
Urban mangroves are increasingly recognized for their important blue-carbon functions, yet their long-term aboveground carbon dynamics under climate extremes and human disturbances remain poorly understood. Here, we developed an integrated framework that
Qian Zhang, Leping Wang, Yangfan Li
doaj   +1 more source

Response distances of wild forest reindeer (Rangifer tarandus fennicus Lönnb.) and semi-domestic reindeer (R. t. tarandus L.) to direct provocation by a human on foot/snowshoes

Rangifer, 2013
The objective of the study was to examine response distances of wild forest reindeer (Rangifer tarandus fennicus Lönnb.) and semi-domestic reindeer (R. t.
Mauri Nieminen
doaj   +1 more source

Human Reproduction and Disturbed Genomic Imprinting

Genes
Genomic imprinting is a specific mode of gene regulation which particularly accounts for the factors involved in development. Its disturbance affects the fetus, the course of pregnancy and even the health of the mother. In children, aberrant imprinting signatures are associated with imprinting disorders (ImpDis).
openaire   +3 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Habitat Selection and Heterospecific Flocking Associations of a Single Male Scaly-Sided Merganser (Mergus squamatus) over Three Winter Seasons in Northern China

Animals
The Scaly-sided Merganser (Mergus squamatus) is an endangered duck endemic to East Asia. It usually gathers in single-species flocks through winter. Existing field records focus almost entirely on southern winter flocks.
Yongbin Zhao, Yanan Hao, Bing Liu, Guodong Yi, Jun Liu, Zhigao Liu   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

What does the fox select? Spatial ecology of Rocky Mountain red fox during peaks and troughs of human recreation

Ecosphere
Understanding animal behavior at the population level can be challenging, especially in the presence of intraspecific variation in behavioral tactics. Individuals within a population often vary with respect to resource exploitation and use, which may be ...
Emily N. Burkholder, John Stephenson, Sarah Hegg, David Gustine, Joseph D. Holbrook   +4 more
doaj   +1 more source

Activity Rhythms of Muntiacus vaginalis in Baiyun Mountain Scenic Area of Guangzhou Based on Camera Trapping

Redai dili
As the only large mammal in Baiyun Mountain Scenic Area, Muntiacus vaginalis is a critical part of that forest ecosystem. Their activity rules and habitat adaptability are the basis of assessing the population status.
Tong Fuchun, Li Renjie, Liu Fangming, Zheng Qinwen, Yi Jiaying, Lin Yan, Peng Yougui   +6 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source