Results 211 to 220 of about 2,157,299 (268)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Use of Commercially Available Large Language Models to Generate Information Leaflets on Post-Intensive Care Syndrome: Clinical Utility Assessment. [PDF]

JMIR Form Res
Hata N, Oami T, Kawakami E, Hanai A, Nakada TA.   +4 more
europepmc   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

A first-in-human evaluation of the safety and immunogenicity of SCB-2019, an adjuvanted, recombinant SARS-CoV-2 trimeric S-protein subunit vaccine for COVID-19 in healthy adults; a phase 1, randomised, double-blind, placebo-controlled trial

, 2020
Richmond P, Hatchuel L, Dong M, Ma B, Hu B, Smolenov I, Li P, Liang P, Han HH, Liang J, Clemens R.   +10 more
europepmc   +1 more source

Between Help and Harm: An Evaluation Study of Mental Health Crisis Handling by Large Language Models. [PDF]

JMIR Ment Health
Arnaiz-Rodriguez A, Baidal M, Derner E, Annable JL, Ball M, Ince M, Perez Vallejos E, Oliver N.   +7 more
europepmc   +1 more source

Can small language models handle context-summarized multi-turn customer-service QA? A synthetic data-driven comparative evaluation. [PDF]

Front Artif Intell
Cooray L, Sumanathilaka D, Venkatesh Raju P.   +2 more
europepmc   +1 more source

Blinded, bias-controlled multi-rater evaluation of human-versus-AI brain metastasis segmentation using a hybrid foundation-model framework. [PDF]

Med Phys
Han Y, Zhu E, Mekdash MHA, Awad O, Pathak P, Liang S, Hamstra DA, Zhang X, Siddiqui ZA, Sun B.   +9 more
europepmc   +1 more source

The value management cycle as a sustainable HRM framework: insights from Chinese Huawei's practices of value creation, evaluation, and distribution. [PDF]

Front Psychol
Liang R.
europepmc   +1 more source