Results 181 to 190 of about 10,990,389 (308)

Author Correction: Zinc isotopes from archaeological bones provide reliable trophic level information for marine mammals

Communications Biology, 2021
Jeremy McCormack, Paul Szpak, Nicolas Bourgon, Michael Richards, Corrie Hyland, Pauline Méjean, Jean-Jacques Hublin, Klervia Jaouen   +7 more
doaj   +1 more source

Cooperative Breeding as a Likely Early Catalyst of Human Evolution. [PDF]

Evol Anthropol
Burkart JM, Cerrito P, Natalucci G, van Schaik CP.   +3 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

The Price of Human Evolution: Cancer-Testis Antigens, the Decline in Male Fertility and the Increase in Cancer. [PDF]

Int J Mol Sci, 2023
Erenpreisa J, Vainshelbaum NM, Lazovska M, Karklins R, Salmina K, Zayakin P, Rumnieks F, Inashkina I, Pjanova D, Erenpreiss J.   +9 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Author Correction: New perspectives on Neanderthal dispersal and turnover from Stajnia Cave (Poland)

Scientific Reports, 2022
Andrea Picin, Mateja Hajdinjak, Wioletta Nowaczewska, Stefano Benazzi, Mikołaj Urbanowski, Adrian Marciszak, Helen Fewlass, Marjolein D. Bosch, Paweł Socha, Krzysztof Stefaniak, Marcin Żarski, Andrzej Wiśniewski, Jean‑Jacques Hublin, Adam Nadachowski, Sahra Talamo   +14 more
doaj   +1 more source

The genetic architecture of human cerebellar morphology supports a key role for the cerebellum in human evolution and psychopathology. [PDF]

Commun Biol
Moberget T, van der Meer D, Bahrami S, Roelfs D, Frei O, Kaufmann T, Fernandez-Cabello S, Kim M, Wolfers T, Diedrichsen J, Smeland OB, Shadrin A, Dale A, Andreassen OA, Westlye LT.   +14 more
europepmc   +1 more source

Dental calculus: A repository of bioinformation indicating diseases and human evolution. [PDF]

Front Cell Infect Microbiol, 2022
Li Q, Luo K, Su Z, Huang F, Wu Y, Zhou F, Li Y, Peng X, Li J, Ren B.   +9 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Does Amyotrophic Lateral Sclerosis (ALS) Have Metabolic Causes from Human Evolution? [PDF]

Cells
Spedding M.
europepmc   +1 more source