Results 181 to 190 of about 3,134,757 (286)

Fossil ribcages of Homo sapiens provide new insights into modern human evolution. [PDF]

Commun Biol
López-Rey JM, Crevecoeur I, May H, Nadel D, Palancar CA, Gómez-Recio M, García-Martínez D, Bastir M.   +7 more
europepmc   +1 more source

Editorial: A 150 years' celebration of Darwin's book on human evolution and sexual selection: its legacy and future prospects. [PDF]

Front Psychol, 2023
Varella MAC, Salmon C, Dixson BJW, Butovskaya M, Pinto A, Pawlowski B, Weisfeld CC, Valentova JV.   +7 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

The Search for Love in Human Evolution: Primate Social Bonds and a New Science of Emotion. [PDF]

Am J Biol Anthropol
Sandel AA.
europepmc   +1 more source

Human-specific genetics: new tools to explore the molecular and cellular basis of human evolution. [PDF]

Nat Rev Genet, 2023
Pollen AA, Kilik U, Lowe CB, Camp JG.
europepmc   +1 more source

Genetic Analysis of Human Evolution: The Case of Oceania [PDF]

, 2012
Wollstein, Andreas
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

The activity and expression of adenylosuccinate lyase were reduced during modern human evolution, affecting brain and behavior. [PDF]

Proc Natl Acad Sci U S A
Ju XC, Lee SY, Ågren R, Machado LC, Xing J, Azama C, Roy MC, Endo T, Huttner W, Siepel A, Fukunaga I, Zeberg H, Pääbo S.   +12 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Models of animal coalitions and their implications for human evolution. [PDF]

Proc Biol Sci
Ihara Y.
europepmc   +1 more source