Results 81 to 90 of about 3,134,757 (286)
Evolution of science II: Insights into working of Nature
We attempt to provide a comprehensive model of evolution of science across millennia taking into account the contributions of other intellectual traditions, cultural value system and increasing in sophistication of humans in their study of nature.
Vahia, M N
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Applying Biochar Mineral Complex to Minimise Nutrient Leaching and Increase Economic Benefits
Biochar mineral complex (BMC) can improve nutrient use efficiency (NUE) and reduce nutrient leaching, but the optimal application form and rate of application in soilless cropping systems remain unclear.
Lakmini Dissanayake +7 more
doaj +1 more source
Evolution and Mirror Neurons. An Introduction to the Nature of Self-Consciousness [PDF]
Self-consciousness is a product of evolution. Few people today disagree with the evolutionary history of humans. But the nature of self-consciousness is still to be explained, and the story of evolution has rarely been used as a framework for studies on ...
Menant, Christophe
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Evolution of retrocopies in the context of HUSH silencing
Retrotransposition is one of the main factors responsible for gene duplication and thus genome evolution. However, the sequences that undergo this process are not only an excellent source of biological diversity, but in certain cases also pose a threat ...
Joanna Kozłowska-Masłoń +3 more
doaj +1 more source
Natural Selection and the Origin of Economic Growth [PDF]
This research develops an evolutionary growth theory that captures the interplay between the evolution of mankind and economic growth since the emergence of the human species.
Galor, Oded, Moav, Omer
core
Naturalism, Evolution and Culture [PDF]
In my essay, I will argue that evolution does not undermine naturalism. This is because Alvin Plantinga’s evolutionary argument against naturalism rests on a false and unmotivated premise and is thus invalid.
Wittwer, Silvan
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source

