Results 101 to 110 of about 10,990,389 (308)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Evolution of human–robot relationships
Since the integration of industrial robots into extensive production lines, there has been a significant emphasis among researchers and engineers on the development of human–robot relationships.
Zheng, Pai,, Wang, Lihui,, Li, Shufei,
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Genes, culture and agriculture : an example of human niche construction [PDF]
, 2012 K. N. Laland was supported by an ERC Advanced Grant (EVOCULTURE).Theory and empirical data from a variety of disciplines strongly imply that recent human history involves extensive gene-culture coevolution, much of it as a direct result of human ...
Laland, Kevin Neville +7 more
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FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Novel phylogenetic algorithm to monitor human tropism in Egyptian H5N1-HPAIV reveals evolution toward efficient human-to-human transmission [PDF]
, 2013 Years of endemic infections with highly pathogenic avian influenza (HPAI) A subtype H5N1 virus in poultry and high numbers of infections in humans provide ample opportunity in Egypt for H5N1-HPAIV to develop pandemic potential.
Ursula Dietrich (351656) +32 more
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Science, evolution and schooling in South Africa
, 2015 This first research project deals with the Human Genome Project, the genetic sequencing exercise of humanity. The extraordinary international project will add new, and undo old, knowledge about our evolution as a species.
Lever, J.
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How can a multimodal approach to primate communication help us understand the evolution of communication? [PDF]
, 2013 Scientists studying the communication of non-human animals are often aiming to better understand the evolution of human communication, including human language.
Waller, B. +12 more
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