Results 241 to 250 of about 6,102,032 (312)

Mechanoregulatory Effects of Cell‐Scale Microwells on Epithelial Cell Phenotype

Advanced Functional Materials, EarlyView.
In small polycaprolactone microwells, A549 epithelial cells span well edges, in contrast to cells growing on flat substrates. Focal adhesion sites (yellow) concentrate at topographic boundaries, while cytoskeletal tension (magenta stress fibers) is transmitted to the nucleus (blue), reducing nuclear sphericity.
Ruiwen He, Wang Sik Lee, Phattadon Yajan, Aaron Lee, Mauro Sousa de Almeida, Sandeep Keshavan, Jozef Adamcik, Céline Loussert‐Fonta, Dimitri Vanhecke, Barbara Rothen‐Rutishauser, Alke Petri‐Fink   +10 more
wiley   +1 more source

Biointerface Membranes Orchestrating Site‐Specific Osteoimmunomodulatory and Antibacterial Effects for Enhanced Osseous Regeneration in Periodontal Therapy

Advanced Functional Materials, EarlyView.
Here, a biointerface membrane engineered with site‐specific interfacial properties is developed. During implantation between gingival and bone defect, the membrane creates a pro‐osteogenic microenvironment, precisely modulates cellular activities at each biointerface, and facilitates the orchestration of complex healing events, ultimately leading to ...
Yuwei Zhu, Tingting Wang, Jing Zhu, Bingtian Zhao, Bingyang Dai, Xiaoyue Zhang, Wei Liu, Cheng Yang, Cheng Dong, Ren Liu, Lei Zhao, Jun Wang, Peilei Shi, To Ngai   +13 more
wiley   +1 more source

Nanothermometry in Living Cells: Physical Limits, Conceptual and Material Challenges

Advanced Functional Materials, EarlyView.
Heat and temperature are fundamental to life. When nanothermometers began probing regions as small as a living cell, they triggered controversial claims of large intracellular temperature gradients. We review physical constraints energy‐conservation, entropy production, thermodynamic fluctuations, and molecular dynamics.
Taras Plakhotnik
wiley   +1 more source

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NOTES: Human Experience

Gastrointestinal Endoscopy Clinics of North America, 2008
Human natural orifice translumenal endoscopic surgery (NOTES) is already being reported from numerous centers, and the results seem promising. There are key issues to be addressed and benefits over traditional safe procedures need to be demonstrated. Interestingly, however, human NOTES seem to be progressing at a fast pace compared with the evolution ...
G V, Rao, D Nageshwar, Reddy, Rupa, Banerjee   +2 more
openaire   +2 more sources

The trapped human experiment

Journal of Breath Research, 2011
This experiment observed the evolution of metabolite plumes from a human trapped in a simulation of a collapsed building. Ten participants took it in turns over five days to lie in a simulation of a collapsed building and eight of them completed the 6 h protocol while their breath, sweat and skin metabolites were passed through a simulation of a ...
Huo, R., Agapiou, Agapios, Bocos-Bintintan, V., Brown, L. J., Burns, C., Creaser, C. S., Devenport, N. A., Gao-Lau, B., Guallar-Hoyas, C., Hildebrand, L., Malkar, A., Martin, H. J., Moll, V. H., Patel, P., Ratiu, A., Reynolds, J. C., Sielemann, S., Slodzynski, R., Statheropoulos, Miltiades K., Turner, M. A., Vautz, W., Wright, V. E., Thomas, Charles Lawrence Paul, Huo, R., Agapiou, Agapios, Bocos-Bintintan, V., Brown, L. J., Burns, C., Creaser, C. S., Devenport, N. A., Gao-Lau, B., Guallar-Hoyas, C., Hildebrand, L., Malkar, A., Martin, H. J., Moll, V. H., Patel, P., Ratiu, A., Reynolds, J. C., Sielemann, S., Slodzynski, R., Statheropoulos, Miltiades K., Turner, M. A., Vautz, W., Wright, V. E., Thomas, Charles Lawrence Paul   +45 more
openaire   +4 more sources

Sketching the Human Experience

Journal of Clinical Oncology, 2014
DOI: 10.1200/JCO.2013.54.7323 “I’ve always wanted to draw the human body. Can you teach me?” Paul asked before I had the chance to put down my sketchbook and pencils. “It’s the most difficult thing to draw” he continued, leaving me to hurriedly introduce myself as the art therapy student in the psycho-oncology department.
Kruti, Hawkins, Casey L, O'Brien, Justin L, Dwyer   +2 more
openaire   +2 more sources