Results 181 to 190 of about 12,069,454 (281)

Mitochondrial Distress Signals at the Heart-Liver Interface: Molecular Links Between MASLD and Heart Failure. [PDF]

Int J Mol Sci
Yang X, Cheng K, Chen C, Zhang Y, Wang DW.   +4 more
europepmc   +1 more source

β‐Adducin Restrains PLA2G4A‐Dependent Lysosomal Membrane Permeabilization and Neuronal Death in Ischemic Stroke

Advanced Science, EarlyView.
This study identifies β‐adducin as a regulator of lysosomal integrity in ischemic neurons. Ischemia‐associated FTO loss increases m6A modification and destabilizes Add2 mRNA, reducing β‐adducin expression and promoting PLA2G4A accumulation at lysosomes.
Hui‐qin Li, Pin‐yi Liu, Dan Wu, Fei‐yu Ma, Yi Bai, Sheng‐nan Xia, Hai‐yan Yang, Xin‐yu Bao, Yun Xu, Xiang Cao   +9 more
wiley   +1 more source

Irisin in Cardiovascular Health and Disease: A Review of Its Function as a Biomarker and Therapeutic Target in Atherosclerosis and Related Conditions. [PDF]

Curr Issues Mol Biol
Dabravolski SA, Shityakov S, Mitkin NA, Rozhkova UV, Antonov SA, Utkina AS, Kovyanova TI.   +6 more
europepmc   +1 more source

Ionically Counter‐Programmable Phase‐Separation of Superstable Star‐Biopolyamide Coacervates for Electrothermally‐Responsive Pseudosolid Smart Windows

Advanced Science, EarlyView.
We develop bio‐based, star‐branched polyamides from itaconic acid and cadaverine with tunable lower critical solution temperature (LCST) transitions for dynamic solar modulation. Specific metal ion coordination with pyrrolidone moieties drives precise phase transitions via calcium‐induced salting‐in and sodium‐induced salting‐out mechanisms. Formulated
Jie Liu, Xiaotian Zhu, Jinjian Hou, Jinze Du, Mohammad Asif Ali, Maiko K. Okajima, Tatsuo Kaneko   +6 more
wiley   +1 more source

The Heart-Kidney Axis in Heart Failure and Chronic Kidney Disease: Mechanisms, Mediators, and Therapeutic Implications. [PDF]

Biomolecules
Fan A, Chen X, Yang K, Ma X, Gao H, Wang B, Fan G, Li L.   +7 more
europepmc   +1 more source

Catalytic Luminescent Polymer Micromotors With Shape‐Programmed Motion

Advanced Science, EarlyView.
A Janus micromotor is designed with an SiO2/Ti/ITO/PFN‐Br/Pt heterostructure with an engineered energy level. The ITO conductive interlayer facilitates efficient charge separation, generating interfacial electric fields and ionic gradients for enhanced light‐driven propulsion.
Yuyang Zhang, Wenyang Huang, Xinwen Gao, Yuhan He, Fei Huang, Tingting Yu   +5 more
wiley   +1 more source

Creatine supplementation and respiratory muscle function in health and disease: translational insights from human to mouse. [PDF]

ERJ Open Res
Price OJ, Brown J, Storey E, Turner L, Johnson M, Sharpe G, Wheatcroft SB, Yuldasheva N, Hendrickse PW, Pereira MG, Bowen TS.   +10 more
europepmc   +1 more source

HECTD1 Directs HIF‐1α to Facilitate Intestinal Inflammation and Carcinogenesis via Promoting Th17 Differentiation and Glycolysis

Advanced Science, EarlyView.
HECTD1 emerges as an upstream amplifier of Th17 metabolic programming by promoting K63‐linked ubiquitination of IGF2BP3 and enhancing HIF‐1α translation. HIF‐1α reciprocally drives HECTD1 transcription, establishing a positive regulatory loop that sustains glycolysis and Th17 differentiation.
Shuiyu Xu, Qiaoqiao Han, Feixiang Wang, Yuerong Zhang, Haoran Feng, Kun Liu, Fang Xiu Luo, Fei Yuan, Xuesong Zhao, Xiaoyan Yu, Haiyan Huang, Qiang Zou, Ren Zhao   +12 more
wiley   +1 more source

Impaired antigen clearance of macrophages associates with heart failure and non-obstructive azoospermia: insights from transcriptomics, in silico knockout, and <i>in vitro</i> validation. [PDF]

Front Immunol
Zhao Z, Li R, Li K, Zhang R, Tian J, Teng D, Zhou X, Jia B, Yuan X, Xin H.   +9 more
europepmc   +1 more source

Black Silicon for Solar Fuels

Advanced Science, EarlyView.
Black silicon couples broadband light harvesting with high‐surface‐area catalytic interfaces, offering a versatile photoelectrode platform for solar‐fuel production. Reaction‐specific analysis highlights trade‐offs involving recombination, chemical instability, catalyst‐induced optical shielding, competing reactions, and mass transport.
Neul Ha, Kaiying Wang, Wooseok Yang
wiley   +1 more source