Results 21 to 30 of about 87,309 (258)

A comprehensive analysis of human factors in maritime accidents by applying SHIELD HF Taxonomy [PDF]

, 2021
Maritime accidents remain a concern in our society despite of the continuous improvement on safety measures. With the aim to contribute to current safety measures, this paper proposes to utilise the Safety Human Incident & Error Learning Database (SHIELD) Human Factors (HF) Taxonomy, which was developed in the context of the European Union SAFEMODE ...
Navas de Maya, Beatriz, Ramirez Marengo, Clementina, Giagloglou, Evanthia, Kurt, Rafet Emek, Turan, Osman, Stroeve, Sybert, Pozzi, Simone   +6 more
openaire   +1 more source

Halofuginone has anti-proliferative effects in acute promyelocytic leukemia by modulating the transforming growth factor beta signaling pathway. [PDF]

PLoS ONE, 2011
Promyelocytic leukemia-retinoic acid receptor alpha (PML-RARα) expression in acute promyelocytic leukemia (APL) impairs transforming growth factor beta (TGFβ) signaling, leading to cell growth advantage. Halofuginone (HF), a low-molecular-weight alkaloid
Lorena L de Figueiredo-Pontes, Patricia A Assis, Bárbara A A Santana-Lemos, Rafael H Jácomo, Ana Sílvia G Lima, Aglair B Garcia, Carolina H Thomé, Amélia G Araújo, Rodrigo A Panepucci, Marco A Zago, Arnon Nagler, Roberto P Falcão, Eduardo M Rego   +12 more
doaj   +1 more source

Does Human Cognition Allow Human Factors (HF) Certification of Advanced Aircrew Systems? [PDF]

, 2000
This paper has examined the requirements of HF specification and certification within advanced or complex aircrew systems. It suggests reasons for current inadequacies in the use of HF in the design process, giving some examples in support, and suggesting an avenue towards the improvement of the HF certification process.
openaire   +1 more source

Mesenchymal stem cells from human amniotic membrane differentiate into cardiomyocytes and endothelial-like cells without improving cardiac function after surgical administration in rat model of chronic heart failure [PDF]

Journal of Cardiovascular and Thoracic Research, 2019
Introduction: Human amnion-derived mesenchymal stem cells (hAMSCs) have been used in the treatment of acute myocardial infarction. In the current study, we investigated the efficacy of hAMSCs for the treatment of chronic model of myocardial ischemia and ...
Fazel Gorjipour, Ladan Hosseini-Gohari, Alireza Alizadeh Ghavidel, Seyed Javad Hajimiresmaiel, Nasim Naderi, Amir Darbandi Azar, Hamidreza Pazoki-Toroudi   +6 more
doaj   +1 more source

The integration of Human Factors (HF) in the SAR process training course text [PDF]

, 1995
This text provides the technical basis for a two-day course on human factors (HF), as applied to the Safety Analysis Report (SAR) process. The overall objective of this text and course is to: provide the participant with a working knowledge of human factors-related requirements, suggestions for doing a human safety analysis applying a graded approach ...
openaire   +2 more sources

Prognostic Significance and Biologic Associations of Senescence‐Associated Secretory Phenotype Biomarkers in Heart Failure

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The role of cellular senescence in human heart failure (HF) remains unclear. The senescence‐associated secretory phenotype (SASP) is composed of proteins released by senescent cells.
Oday Salman, Payman Zamani, Lei Zhao, Marie Joe Dib, Sushrima Gan, Joe David Azzo, Bianca Pourmussa, Arthur Mark Richards, Ali Javaheri, Douglas L. Mann, Ernst Rietzschel, Manyun Zhao, Zhaoqing Wang, Christina Ebert, Laura Liu, Kushan L. Gunawardhana, Danielle Greenawalt, Leon Carayannopoulos, Ching‐Pin Chang, Vanessa van Empel, Joseph Gogain, Peter H. Schafer, David A. Gordon, Francisco Ramirez‐Valle, Thomas P. Cappola, Julio A. Chirinos   +25 more
doaj   +1 more source

Oncostatin M mediates cardioprotection via angiogenesis in ischemic heart disease

American Heart Journal Plus, 2023
Objective: Oncostatin M (OSM) is an inflammatory cytokine belonging to the interleukin-6 family member, which plays an important role in various cardiovascular diseases.
Shohei Ikeda, Koichi Sato, Morihiko Takeda, Mariko Shinozaki, Keita Miki, Michinori Hirano, Koji Fukuda, Nobuyuki Shiba   +7 more
doaj   +1 more source

Human Factor Modelling in the Risk Assessment of Port Manoeuvers [PDF]

TransNav, 2015
The documentation of human factor influence on the scenario development in maritime accidents compared with expert methods is commonly used as a basis in the process of setting up safety regulations and instructions.
Teresa Abramowicz-Gerigk, Andrzej Hejmlich   +1 more
doaj   +1 more source

Chamber-specific transcriptional responses in atrial fibrillation

JCI Insight, 2020
Atrial fibrillation (AF) is the most common cardiac arrhythmia, yet the molecular signature of the vulnerable atrial substrate is not well understood.
Catherine E. Lipovsky, Jesus Jimenez, Qiusha Guo, Gang Li, Tiankai Yin, Stephanie C. Hicks, Somya Bhatnagar, Kentaro Takahashi, David M. Zhang, Brittany D. Brumback, Uri Goldsztejn, Rangarajan D. Nadadur, Carlos Perez-Cervantez, Ivan P. Moskowitz, Shaopeng Liu, Bo Zhang, Stacey L. Rentschler   +16 more
doaj   +1 more source

The Relationship Between Physical Activity and Left Ventricular Remodeling in Childhood Cancer Survivors Treated With Anthracyclines: A Cross‐Sectional Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Anthracycline‐related cardiac remodeling precedes heart failure in childhood cancer survivors. The objectives of this study were to determine the relationships between patient‐specific factors, moderate‐to‐vigorous physical activity (MVPA), and cardiac remodeling.
Hari K. Narayan, Sitong Chen, F. Lennie Wong, Nathan Young, Anna Qi, Christopher Davis, Sanjeet Hegde, Nicholas Gloude, Kasey J. Leger, Kelly D. Getz, Francisco Contijoch, Kirsten Ness, Bonnie Ky, Dennis Kuo, Sheri J. Hartman, Saro H. Armenian   +15 more
wiley   +1 more source