Results 231 to 240 of about 18,923,181 (308)

Tools or culture? Human factors, not technology, drive cesarean section rates for suspected fetal distress. [PDF]

Int J Gynaecol Obstet
Ragusa A, Meloni A, Maini I, Lo Re A, De Luca C, D'Avino S, Svelato A, Soncini E, Ficarola F, Matta M, Rinaldo D.   +10 more
europepmc   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Strengthening pediatric cardiac surgical safety through human factors: Anesthesia perspectives. [PDF]

Ann Pediatr Cardiol
Gopalakrishnan RM.
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

The role of human factors in paramedics' clinical judgement - A modified Delphi study. [PDF]

PLoS One
Poranen A, Kouvonen A, Nordquist H.
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Human Factors in Airway Management: Designing Systems for Safer, Team-Based Care. [PDF]

J Clin Med
Gómez-Ríos MÁ, Michalek P, Gaszyński T, Van Zundert AAJ.   +3 more
europepmc   +1 more source

Human factors in digital manufacturing technology adoption: a workforce perspective. [PDF]

Int J Adv Manuf Technol
Oostveen AM, Eimontaite I, Fletcher S.
europepmc   +1 more source

Comparative Use Human Factors Study of a Manual vs. A Partially Automated Pen Injector for GLP-1 Receptor Agonist Delivery. [PDF]

Clin Pharmacol Ther
Natarajan K, Clerman A, Soosaar J, Sye S, Giacomini J, Conti DS, Bhalodia A, Flint J, Chattopadhyay S, Hartka K, Lieu S, Feibus K, Kim S, Klingensmith R, Luke MC.   +14 more
europepmc   +1 more source