Results 91 to 100 of about 64,267 (215)

Cumulative effects of human footprint, natural features and predation risk best predict seasonal resource selection by white-tailed deer. [PDF]

Sci Rep, 2022
Darlington S, Ladle A, Burton AC, Volpe JP, Fisher JT.   +4 more
europepmc   +1 more source

Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

Advanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du, Changyu Pi, Kai Hong, Le Gao, Xin Wu   +4 more
wiley   +1 more source

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

Advanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu, Miaozhan Zou, Yunshang Bai, Yang He, Zhihao Jin, Baozhi Yang, Jinjin Du, Pei Ouyang, Yuanyuan Cai, Yuheng Zhang, Bingying Du, Chengcheng Ge, Jian‐an Gong, Xiaoyu Li, Yuanyi Zheng, Jing Ding, Bo Peng, Yanxia Rao   +17 more
wiley   +1 more source

NeuroSuite for Long‐Term Functional and Structural Studies of Air‐Liquid Interface Cerebral Organoids

Advanced Science, EarlyView.
NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider, Sagnik Middya, Daniel J. Lloyd‐Davies‐Sánchez, Nino F. Läubli, Sulay Vora, Jakob Träuble, Rohan N. Krajeski, Yuqing Feng, Daniel Duncko, Josiah S. Riley, Rubén Ruiz‐Mateos Serrano, Ole Paulsen, Madeline A. Lancaster, George G. Malliaras, Gabriele S. Kaminski Schierle   +14 more
wiley   +1 more source

Comprehensive Analysis of the Impact of Climate Change and Human Activities on the Distribution of Five Fritillaria Species Using the Optimized Maxent Model

Ecology and Evolution
With climate change and the influence of human activities, species are likely to migrate or even go extinct. Five Fritillaria species, a well‐known traditional Chinese medicinal plant, are rarer due to overharvesting. This study employed the Maxent model
Yuanyuan Li, Qinghe Wang, Rong Ding, Xiaofen Liu, Sijing Liu, Jing Bai, Shuqi Niu, Jinlin Guo   +7 more
doaj   +1 more source

Management Effectiveness of Protected Areas in Mitigating Human Disturbance: A Case Study of the Qilian Mountains for 2000–2022

Land
Evaluating the management effectiveness of protected areas (PAs) is critical for refining conservation strategies. One of the key components in the management of PA is the regulation of human disturbance.
Yun Li, Jian Gong, Shicheng Li
doaj   +1 more source

Sustainable Fabrication of Tailored Bone Substitutes: From High‐Throughput Scaffold Manufacturing, Scaled‐Up HMSC Expansion to Dynamic Cultivation in a Perfusion Bioreactor

Advanced Science, EarlyView.
ABSTRACT The demand for off‐the‐shelf biocompatible bone substitutes has driven the development of numerous independent in vitro technologies to generate products resembling physiological tissues. Due to technical challenges and overly simplified cultivation approaches/niches, the end‐products are often uniformly shaped and inferior to native bone ...
Franziska Braun, Anna Paříková, Sandra Rother, Martin Kantor, Salman Muhammad Ilyas, Ricardo Bernhardt, Pavel Ndjawa Yomi, Jaromír Havlica, Revathi Appali, Benjamin Kruppke, Poh Soo Lee   +10 more
wiley   +1 more source

Polychip‐A High‐Throughput Droplet Microfluidics Platform for Interrogating Microbial Interactions

Advanced Science, EarlyView.
Polychip, a fully integrated droplet microfluidics platform, enables high‐throughput, single‐cell resolution screening of polymicrobial interactions. By seamlessly combining six automated microfluidics operations on a single chip, the system accelerates antimicrobial discovery by 11 to 14 times compared to traditional robotic methods.
Jeong Jae Han, Adrian Ryan Guzman, Aifen Zhou, Han Zhang, Rohit Gupte, Haemin Jung, Kaylee Delgado, Sini Skariah, Ali Sultan, Arul Jayaraman, Paul de Figueiredo, Arum Han   +11 more
wiley   +1 more source

Ethical Precision in Nanoscale Brain Interfacing

Advanced Science, EarlyView.
As brain interfaces approach the nanoscale, precision no longer only measures—it knows, predicts, and potentially reshapes the mind. This work argues that traditional ethics fails under such conditions and proposes a shift toward continuous, operation‐based governance using the recovery–discovery framework to track, constrain, and responsibly steer ...
Guilherme Wood
wiley   +1 more source

Analysis of Spatio-Temporal Relationship Between Ecosystem Services and Human Footprints Under Different Human Activity Gradients: A Case Study of Xiangjiang River Basin

Remote Sensing
Clarifying the relationship between human activities and the provision of ecosystem services has received significant interest in recent years because of a growing need for sustainable socio-ecological system development.
Songjia Chen, Junhua Yan, Yingping Wang, Zhongbin Chang, Guangcan Yu, Jie Li, Jun Jiang, Linhua Wang, Shuo Zhang, Yang Chen, Pingping Xu, Cong Wang, Xinyu Yan, Chunyi Liu, Sihui Qiu, Siyuan Fanrong, Mengxiao Yu   +16 more
doaj   +1 more source