Results 141 to 150 of about 63,965 (268)

Nanozyme‐Reinforced miR‐197‐3p Delivery Resets Metabolic and Senescence Pathways to Rejuvenate Osteoarthritic Cartilage

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a progressive and disabling joint disease driven by oxidative stress, chondrocyte senescence and extracellular matrix (ECM) degradation, yet lacks effective disease‐modifying treatments. In this study, we identified miR‐197‐3p as a previously unrecognized, cartilage‐protective miRNA significantly downregulated in both ...
Xuejie Cai, Zehui Lv, Chen Zhang, Xingdong Yang, Ruoying Wang, Yixin Bian, Jiawei Xu, Han Wang, Yingjie Wang, Long Bai, Jiacan Su, Xisheng Weng   +11 more
wiley   +1 more source

Human Footprint and Forest Disturbance Reduce Space Use of Brown Bears (Ursus arctos) Across Europe. [PDF]

Glob Chang Biol
Hertel AG, Parres A, Frank SC, Renaud J, Selva N, Zedrosser A, Balkenhol N, Maiorano L, Fedorca A, Dutta T, Bogdanović N, Bragalanti N, Chiriac S, Ćirović D, Ciucci P, Domokos C, Fedorca M, Filacorda S, Finďo S, Groff C, de Gabriel Hernando M, Huber D, Ionescu G, Jerina K, Karamanlidis AA, Kindberg J, Kojola I, Mertzanis Y, Palazon S, Pop MI, Psaralexi M, Quenette PY, Sergiel A, Skuban M, Zlatanova D, Zwijacz-Kozica T, De Barba M.   +36 more
europepmc   +1 more source

Enhanced Antibacterial Properties of Lyotropic Liquid Crystalline Nanoparticles via Curvature Modulation

Advanced Science, EarlyView.
Lipid nanostructured particles with increasing negative Gaussian curvature progress from vesicles to P‐cubosomes and D‐cubosomes. This curvature hierarchy enhances interaction with bacterial membranes, promotes membrane remodeling and leakage, and potentiates daptomycin activity against MRSA.
Xiangfeng Lai, Shuhong Wang, Chenguang Ding, Xenia Kostoulias, Anton P. Le Brun, Hsien‐Yi Hsu, Jhih‐Hang Jiang, Yajun Wang, Richard A. Strugnell, Anton Y. Peleg, Hsin‐Hui Shen   +10 more
wiley   +1 more source

Mapping roadless areas in regions with contrasting human footprint. [PDF]

Sci Rep
Hoffmann MT, Ostapowicz K, Bartoń K, Ibisch PL, Selva N.   +4 more
europepmc   +1 more source

Liquid Metals in Radio Frequency Applications: A Review of Physics, Manufacturing, and Emerging Technologies

Advanced Electronic Materials, EarlyView.
This paper reviews the physics of liquid metals in RF devices, including the influence of mechanical strain on resonance as well as fabrication methods and strategies for designing tunable and strain‐tolerant inductors, capacitors, and antennas.
Md Saifur Rahman, William J. Scheideler
wiley   +1 more source

The Human Footprint and Climate Change Shape Current and Future Scenarios of Visceral Leishmaniasis Distribution in Doce River Basin in Brazil. [PDF]

Am J Trop Med Hyg
Monteiro JCL, Ribeiro SP, Vieira Duarte R, Lira-Noriega A, Rojas-Soto OR, Carneiro M, Reis AB, Coura-Vital W.   +7 more
europepmc   +1 more source

Changes in human footprint drive changes in species extinction risk. [PDF]

Nat Commun, 2018
Di Marco M, Venter O, Possingham HP, Watson JEM.   +3 more
europepmc   +1 more source

Gel‐Amin for Improving Extracellular Recordings of Cardiomyocytes in a 3D Microphysiological System

Advanced Electronic Materials, EarlyView.
This work combines a conductive collagen‐based hydrogel with a laser‐cut and assembly technique to fabricate microphysiological systems that improve extracellular recordings of cardiomyocytes in 3D on microelectrode arrays. The inclusion of choline acrylate into GelMA imparts a higher electrical conductivity and improves the signal‐to‐noise ratio of on‐
Dominic Pizzarella, Katelyn Neuman, Nolan Burson, Abigail N. Koppes, Ryan A. Koppes   +4 more
wiley   +1 more source

Estimation of mammalian wildlife density by REM method in a Mediterranean forest ecosystem (Pinus brutia) of Türkiye: how human footprint effects mammal community? [PDF]

BMC Zool
İlemin Y.
europepmc   +1 more source

A late Pleistocene human footprint from the Pilauco archaeological site, northern Patagonia, Chile. [PDF]

PLoS One, 2019
Moreno K, Bostelmann JE, Macías C, Navarro-Harris X, De Pol-Holz R, Pino M.   +5 more
europepmc   +1 more source