Results 121 to 130 of about 63,965 (268)

Managing climate refugia for freshwater fishes under an expanding human footprint. [PDF]

Front Ecol Environ, 2020
Ebersole JL, Quiñones RM, Clements S, Letcher BH.   +3 more
europepmc   +1 more source

The Spatiotemporal Genetic Architecture of Seed Vigor in Upland Cotton

Advanced Science, EarlyView.
Leveraging the semi‐automated SeedRanger platform, we profiled the germination kinetics of 356 cotton accessions at a 30‐min interval. This high‐throughput phenomic approach delineated a temporal genetic network comprising 541 stage‐specific loci. Crucially, functional validation identified FLA2 as a pivotal, auxin‐modulated regulator that orchestrates
Luyao Wang, Jie Dai, Ting Zhao, Shengjun Zhao, Hongyu Wu, Jiaying Pan, Yupeng Hao, Ke Nie, Li Yu, Yumeng Zhu, Xiangyi Zhao, Kai Huang, Mengke Zhang, Yongyan Zhao, Yaping Jiang, Siyuan Wang, Yiling Pan, Yubing Chen, Yilai Lin, Wanghong Shi, Yayuan Deng, Jin Han, Jie Li, Xuan Long, Junbin Wang, Zhiyuan Zhang, Zegang Han, Zhanfeng Si, Lei Ju, Jun Li, Tianzhen Zhang, Ji Zhou, Xueying Guan   +32 more
wiley   +1 more source

Hidden Markov Models reveal a clear human footprint on the movements of highly mobile African wild dogs. [PDF]

Sci Rep, 2020
Creel S, Merkle J, Mweetwa T, Becker MS, Mwape H, Simpamba T, Simukonda C.   +6 more
europepmc   +1 more source

Polymer‐Based Multiparameter Sensing Integrated Photonic Chip for Health Monitoring

Advanced Science, EarlyView.
A monolithic integrated photonic chip simultaneously measures blood glucose, pressure, temperature, ECG, and sweat glucose. Combining multiple Bragg grating sensors, Mach–Zehnder modulators, and an on–‐chip demodulation unit, this compact chip (1 cm × 0.5 cm) offers robust multiparameter detection.
Xiaolin Li, Hongqiang Li, Ming Han, Xin Liu, Mingjun Ding, Ziying Niu, Dongyang Liu, Liyuan Yang, Lizhen Zhang, Francisco Hernández‐Ramírez, Lu Cao, Enbang Li   +11 more
wiley   +1 more source

Understanding the spatial-temporal variation of human footprint in Jiangsu Province, China, its anthropogenic and natural drivers and potential implications. [PDF]

Sci Rep, 2020
Shen F, Yang L, He X, Zhou C, Adams JM.
europepmc   +1 more source

Radiation‐Induced Tumor‐Intrinsic LTβR N‐Glycosylation Suppresses Pyroptosis Through TRIM28‐Mediated PCBP2 SUMOylation to Promote Gastric Cancer Radioresistance

Advanced Science, EarlyView.
Radiotherapy triggers LTβR N‐glycosylation, enhancing its overall protein stability and nuclear retention. This accumulation drives TRIM28‐mediated PCBP2 SUMOylation, suppressing pyroptosis and conferring gastric cancer radioresistance. Therapeutically, a targeted nanoplatform (cRGD‐Lipo@EMD) effectively disrupts this regulatory axis, offering a highly
Weijie Zang, Yunlong Ji, Chunwang Zhou, Xiwen Li, Zhuang Lu, Guangze Zhang, Yu Chen, Wanjiang Xue, Yilin Hu   +8 more
wiley   +1 more source

Synergistic Effect of Gradient Conductivity and Gradient Microstructures Enabled Ultrasensitive and Ultrabroad Linear Flexible Tactile Sensors

Advanced Science, EarlyView.
A design of double gradient effect is proposed to resolve the contradictory optimization on sensitivity and linearity of piezoresistive tactile sensors. The ultrawide linearity is realized by the sequential trigger of pressure‐induced gradient conductivity‐enabled linear current owing to the gradient microstructures.
Yao Fang, Yiwei Wang, Bing Zheng, Liu Yang, Jingyi Yue, Qian Zhou, Jinrong Huang, Yongyun Mao, Qian Li, Jifei Wang, Dongsheng Tang, Yuxin Tang, Bingpu Zhou, Bing Ji   +13 more
wiley   +1 more source

De Novo Designed Minibinders Targeting the GDF15–GFRAL Axis Reverse Cancer Cachexia and Restore Anti‐Tumor Immunity

Advanced Science, EarlyView.
Tumor‐derived GDF15 drives cancer cachexia and suppresses antitumor immunity. Here, de novo designed minibinders targeting the GDF15–GFRAL interface achieve picomolar affinity and potent pathway blockade. The minibinders alleviate cachexia, restore CD8+ T‐cell infiltration, enhance anti–PD‐1 responsiveness, and provide survival benefits across tumor ...
Haitao Wang, Tianzhen Hua, Meiling Wang, Bingbing Meng, Yue Zhang, Chengxu Jiang, Yunhe Gao, Hongqi Yang, Jian Bo   +8 more
wiley   +1 more source

Human Footprint on Tides in Estuaries

Abstract Tides exert strong control over flooding and ecological processes in estuaries, yet their dynamics are often altered by human activities such as dredging and land reclamation. Using archival and modern records from 25 estuaries worldwide, we assess human-driven changes in tidal dynamics over timescales of decades to centuries ...
Joris Beemster, Stefan Talke, Dirk Sebastiaan van Maren, Nathalie Giloy, Wei Zhang, Anna Wünsche, Florent Grasso, A.J.F. (Ton) Hoitink   +7 more
openaire   +1 more source

A Versatile‐Designable Framework for Active and Programmable Shape‐Morphing Soft Matter Systems: From Inverse Design to Closed‐Loop Control

Advanced Science, EarlyView.
A versatile framework integrates addressable electrothermal actuation and strain‐constraint mechanisms to construct programmable shape‐morphing soft matter systems. By combining an analytical inverse design strategy for high‐fidelity 3D surface reconstruction with deep learning‐based closed‐loop control, this approach enables zero‐energy shape locking,
Kai Liu, Peiling Xie, Ruitong Song, Banghan Liu, Rui Guo, Jiu‐an Lv   +5 more
wiley   +1 more source