Results 71 to 80 of about 8,024,974 (292)

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Model-driven statistical analysis of human gait motion

, 2002
We describe a new method for analyzing and extracting human gait motion by combining statistical methods with image processing. The periodic motion of human gait is modeled by trigonometric-polynomial interpolant functions.
Harris, Chris J, Yoo, Jang H, Nixon, Mark S   +2 more
core   +1 more source

Modelling, stability and biomechanical implications of three DOF passive bipedal gait

Ingeniería e Investigación, 2007
Passive dynamic walkers can achieve a steady gait down an inclined plane simply by the influence of gravity. This article presents the modelling of a 3 DOF passive bipedal walker, searching for a relationship between gait characteristics, the robot’s ...
Máximo Alejandro Roa Garzón, Camilo Villegas, Diego Alexander Garzón Alvarado   +2 more
doaj  

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Skeleton-Based Abnormal Gait Detection

Sensors, 2016
Human gait analysis plays an important role in musculoskeletal disorder diagnosis. Detecting anomalies in human walking, such as shuffling gait, stiff leg or unsteady gait, can be difficult if the prior knowledge of such a gait pattern is not available ...
Trong-Nguyen Nguyen, Huu-Hung Huynh, Jean Meunier   +2 more
doaj   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source

Walking on Virtual Surface Patterns Leads to Changed Control Strategies

Sensors
Inclusive design does not stop at removing physical obstacles such as staircases. It also involves identifying architectural features that impose sensory burdens, such as repetitive visual patterns that are known to potentially cause dizziness or visual ...
Maximilian Stasica, Celine Honekamp, Kai Streiling, Olivier Penacchio, Loes van Dam, André Seyfarth   +5 more
doaj   +1 more source

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino, Lavanya Muthukumar, Evan L. Reynolds, Peter Todd, Sinem Ovunc, Sheng Chih Jin, Zitian Tang, Simone Thomas, PNRR Study Group, Ahmet Höke, Brian C. Callaghan, Sarah Berth, Vinay Chaudhry, David Cornblath, Leana Doherty, Lindsey Hayes, Hristelina Ilieva, Thomas Lloyd, Mohammad Khoshnoodi, Brett McCray, Brett Morrison, Bipasha Mukherjee‐Clavin, Lyle Ostrow, Michael Polydefkis, Ricardo Roda, Charlotte Sumner   +25 more
wiley   +1 more source

Human Recognition Based on Gait Poses [PDF]

, 2011
This paper introduces a new approach for gait analysis based on the Gait Energy Image (GEI). The main idea is to segment the gait cycle into some biomechanical poses, and to compute a particular GEI for each pose. Pose-based GEIs can better represent body parts and dynamics descriptors with respect to the usually blurred depiction provided by a general
Raúl Martín-Félez, Ramón Alberto Mollineda, José Salvador Sánchez 0001   +2 more
openaire   +1 more source

Feasibility of Training a Random Forest Model With Incomplete User-Specific Data for Devising a Control Strategy for Active Biomimetic Ankle

Frontiers in Bioengineering and Biotechnology, 2020
Intelligent control strategies for active biomimetic prostheses could exploit the inter-joint coordination of limbs in human gait in order to mimic the functioning of a biological joint.
Sharmita Dey, Takashi Yoshida, Arndt F. Schilling   +2 more
doaj   +1 more source