Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone +8 more
wiley +1 more source
Benchmarking Foot Trajectory Estimation Methods for Mobile Gait Analysis
Mobile gait analysis systems based on inertial sensing on the shoe are applied in a wide range of applications. Especially for medical applications, they can give new insights into motor impairment in, e.g., neurodegenerative disease and help objectify ...
Julius Hannink +5 more
doaj +1 more source
Model-driven statistical analysis of human gait motion
We describe a new method for analyzing and extracting human gait motion by combining statistical methods with image processing. The periodic motion of human gait is modeled by trigonometric-polynomial interpolant functions.
Mark S. Nixon +5 more
core
Dementia Incidence in Individuals With Parkinson's Disease in the Framingham Heart Study
ABSTRACT Limited information exists on incident dementia in individuals with Parkinson's disease (PD) in US community‐based samples. We examined cognitive statuses and PD diagnoses of 183 individuals in the Framingham Heart Study (FHS) to establish incident dementia, mortality rates, associations with sex, age at PD onset, and education level.
Joshi Dookhy +11 more
wiley +1 more source
Multivariate Multiscale Symbolic Entropy Analysis of Human Gait Signals
The complexity quantification of human gait time series has received considerable interest for wearable healthcare. Symbolic entropy is one of the most prevalent algorithms used to measure the complexity of a time series, but it fails to account for the ...
Jian Yu +5 more
doaj +1 more source
A Review of Chinese Academy of Sciences (CASIA) Gait Database As a Human Gait Recognition Dataset
Human Gait as the recognition object is the famous biometrics system recently. Many researchers had focused this subject to consider for a new recognition system.
Basuki, Achmad +2 more
core
Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez +10 more
wiley +1 more source
Gender classification in human gait using support vector machine
We describe an automated system that classifies gender by utilising a set of human gait data. The gender classification system consists of three stages: i) detection and extraction of the moving human body and its contour from image sequences; ii ...
Yoo, Jang, Nixon, Mark, Hwang, D
core
Automatic Gait Recognition by Symmetry Analysis
We describe a new method for automatic gait recognition based on analysing the symmetry of human motion, by using the Generalised Symmetry Operator. This operator, rather than relying on the borders of a shape or on general appearance, locates features ...
Mark S. Nixon +5 more
core +1 more source
Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni +19 more
wiley +1 more source

